Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin +11 more
wiley +1 more source
A versatile large-scale coherent Ising machine from microwave to visible and telecom wavelength bands. [PDF]
Zhang H, Li J, Zhu H.
europepmc +1 more source
Expandable Nanocomposite Shape‐Memory Hemostat for the Treatment of Noncompressible Hemorrhage
A nanocomposite‐coated shape memory foam rapidly expands, accelerates clotting, and reduces blood loss in vivo. Its fast volumetric expansion and strong procoagulant activity make it a promising hemostat for treating deep, noncompressible hemorrhage.
Saptarshi Biswas +12 more
wiley +1 more source
Remembering Professor Chen-Ning Yang: A life of profound brilliance and enduring dedication. [PDF]
Innovation editorial board.
europepmc +1 more source
Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck +8 more
wiley +1 more source
Graphene-Based Nanostructures Produced by Laser Ablation Assisted by Electric Field. [PDF]
Cutroneo M +5 more
europepmc +1 more source
Layer‐Dependent Antiferromagnetic Chern and Axion Insulating States in UOTe
Layer‐dependent topological phases are identified in the van der Waals antiferromagnet UOTe. Ab initio calculations reveal bilayer UOTe as a rare example of high‐temperature antiferromagnetic Chern insulator with quantized Hall conductivity and near‐zero net magnetization, while odd‐layer films exhibit axion‐insulator‐like behavior with quantized spin ...
Sougata Mardanya +10 more
wiley +1 more source
Capturing coherent pseudorotation through conical intersection in photoionized benzene. [PDF]
Liu Z +16 more
europepmc +1 more source
A Self‐Organized Liquid Reaction Container for Cellular Memory
How cells restore epigenetic information lost during replication is not known. This work proposes a mechanism based on the formation of biomolecular condensates. These condensates are induced by the chromosome itself and serve as reaction vessels for reconstructing missing epigenetic markers.
Sukanta Mukherjee +4 more
wiley +1 more source
The path to room-temperature superconductivity: A programmatic approach. [PDF]
Prasankumar RP +15 more
europepmc +1 more source

