Results 111 to 120 of about 1,890,269 (306)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Evolution of self-maintaining cellular information processing networks [PDF]
We examine the role of self-maintenance (collective autocatalysis) in the evolution of computational biochemical networks. In primitive proto-cells (lacking separate genetic machinery) self-maintenance is a necessary condition for the direct reproduction
Decraene, James, McMullin, Barry
core
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
An Intelligent Fleet Condition-Based Maintenance Decision Making Method Based on Multi-Agent [PDF]
According to the demand for condition-based maintenance online decision making among a mission oriented fleet, an intelligent maintenance decision making method based on Multi-agent and heuristic rules is proposed.
Bo Sun, Qiang Feng, Songjie Li
core
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Condition based maintenance optimization for multi-state wind power generation systems under periodic inspection [PDF]
As the wind power system moves toward more efficient operation, one of the main challenges for managers is to determine a cost effective maintenance strategy.
Abdollahzadeh Hadi +3 more
doaj
Editorial Special Issue: PHM for Railway Systems and Mass Transportation
The railway and mass transportation system is composed of industrial goods with substantial capital investments and long life cycles. This applies to rolling stock like trains, locomotives, wagons, and even more to the infrastructure like signaling ...
John Andrews +4 more
doaj +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Prediction of Motor Failure Time Using An Artificial Neural Network
Industry is constantly seeking ways to avoid corrective maintenance so as to reduce costs. Performing regular scheduled maintenance can help to mitigate this problem, but not necessarily in the most efficient way.
Gustavo Scalabrini Sampaio +3 more
doaj +1 more source

