Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Deep Reinforcement Learning for Condition Based Monitoring in Aircraft Planning
, 2019 Dissertação de Mestrado em Engenharia Informática apresentada à Faculdade de Ciências e TecnologiaAtualmente, as manutenções na aviação são maioritariamente pré-programadas ou reactivas.
Ferreira, Pedro Filipe Soares
core
Prediction cost maintenance model of office building based on condition-based maintenance [PDF]
, 2014 Building maintenance costs are continuously increasing as a result of poor maintenance. Consequently, there is an urgent need to develop solutions to reduce the maintenance costs.
Au-Yong, C.P., Ahmad, F., Ali, A.S.
core +1 more source
A Multi-Level Decision Fusion Strategy for Condition Based Maintenance of Composite Structures. [PDF]
Materials (Basel), 2016 Sharif Khodaei Z, Aliabadi MH.
europepmc +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
An optimization method for condition based maintenance of aircraft fleet considering prognostics uncertainty. [PDF]
ScientificWorldJournal, 2014 Feng Q, Chen Y, Sun B, Li S.
europepmc +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source