Results 121 to 130 of about 1,890,269 (306)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Reset Aviation Maintenance Program Study of U.S. Army Aviation [PDF]
, 2011 U.S. Army helicopter maintenance condition is affected by operation environment and high flight hours. Due to the environmental conditions and high operation tempo of Afghanistan and Iraq, U.S. Army Aviation created the RESET aviation maintenance program
Williams, Kristopher B.
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Approximating the Randomized Hitting Time Distribution of a Non-stationary Gamma Process [PDF]
The non-stationary gamma process is a non-decreasing stochastic process with independent increments. By this monotonic behavior this stochastic process serves as a natural candidate for modelling time-dependent phenomena such as degradation. In condition-
Frenk, J.B.G., Nicolai, R.P.
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Estimating the cost of offshore maintenance and the benefit from condition monitoring [PDF]
, 2011 The EU generally, and the UK, Belgium, Netherlands and Germany specifically, have ambitious plans for the large scale installation of offshore wind-power capacity.
Feuchtwang, Julian, Infield, David
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Perbandingan Metode Bina Marga dan Metode PCI (Pavement Condition Index) dalam Penilaian Kondisi Perkerasan Jalan (Studi Kasus : Simpang Lago - Simpang Buatan) [PDF]
, 2018 There are methods that can be used to evaluate pavement conditions, such as Bina Marga and PCI (Pavement Condition Index) methods. In the Bina Marga method, the determination of road condition values are done by summing numbers and values of damage ...
Copricon, D. E. (Deby) +2 more
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A cost-benefit approach for the evaluation of prognostics-updated maintenance strategies in complex dynamic systems [PDF]
, 2016 The implementation of maintenance strategies which integrate online condition data has the potential to increase availability and reduce maintenance costs.
Aizpurua, J. I. +3 more
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