Results 51 to 60 of about 509,143 (264)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
CONDITION BASED MAINTENANCE: STATUS AND FUTURE DIRECTIONS
South African Journal of Industrial Engineering, 2012 <p>ENGLISH ABSTRACT: Research on condition-based maintenance (CBM) spans disciplines and introduces a wide range of concepts. On the basis of statistical analysis of the papers published in major maintenance-related journals, the development of the
S.A. Oke
doaj
Engineering Reports, 2022 This article develops a joint model of condition‐based maintenance (CBM) and economic production quantity (EPQ) for a single‐unit manufacturing system.
Jianhua Yang, Xiao Zhao, Mengying Han
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Condition-Based Maintenance in Facilities Management
Computing in Civil Engineering (2011), 2011 A facility management strategy requires that an organization’s major operational concerns are dealt with, such as: avoiding the risk of catastrophic failures, planning for asset maintenance and reducing the quantity of spare parts and associated inventory costs.
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Maintenance optimization for rolling bearing based on delay time model
International Journal for Simulation and Multidisciplinary Design OptimizationRolling bearings are critical components in rotating machinery, directly influencing system reliability and performance. Bearing failures, driven by stochastic degradation processes, necessitate accurate reliability assessment and maintenance ...
Bui Minh-Hien +4 more
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FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source