Results 61 to 70 of about 509,143 (264)

International Journal of Prognostics and Health Management, ISSN 2153-2648, 2017 019 1 A Condition Based Maintenance Implementation for an Automated People Mover Gearbox

open access: yesInternational Journal of Prognostics and Health Management, 2017
Data-driven condition-based maintenance (CBM) can be an effective predictive maintenance strategy for components within complex systems with unknown dynamics, nonstationary vibration signatures or a lack of historical failure data.
Ali Ashasi-Sorkhabi   +3 more
doaj   +1 more source

Advanced sensor-based maintenance in real-world exemplary cases

open access: yesAutomatika, 2020
Collecting complex information on the status of machinery is the enabler for advanced maintenance activities, and one of the main players in this process is the sensor.
Michele Albano   +8 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Experimental Validation of Motor Current Signature Analysis for a 2HP Induction Motor

open access: yesRevista Facultad de Ingeniería Universidad de Antioquia, 2014
The  use  of  stator  currents  signal  analysis  for  rotating  electrical  machines  monitoring, particularly induction motors, has developed a growing interest, as the information contained in the spectrum of the current signal can indicate the ...
Jabid E. Quiroga   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Diagnosis of computer cooling performance based on multipoint temperature measurements

open access: yesJournal of Thermal Science and Technology, 2017
We propose a method for inferring the condition of factors influencing the temperature of heat-generating components in electronic equipment. Here, “factor” includes cooling components (fans, heat sinks, etc.), intake temperature, and the caloric value ...
Tomoyuki SUZUKI, Tomonao TAKAMATSU
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Automatic creation method of extraction condition of sensor data for anomaly detection based on machine learning

open access: yesNihon Kikai Gakkai ronbunshu, 2015
Anomaly detection methods are becoming important for condition-based maintenance. This paper proposes an automatic creation method of extraction condition of sensor data for an anomaly detection system.
Tomoaki HIRUTA   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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