Results 71 to 80 of about 25,185,059 (276)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Typology of condition based maintenance
Journal of Quality in Maintenance Engineering, 2011 PurposeThe purpose of this paper is the development of an empirically based typology of condition based maintenance (CBM) approaches, including the relevant characteristics and requirements.Design/methodology/approachAn exploratory case study was conducted in a major gas production facility.
Veldman, Jasper +2 more
openaire +4 more sources
International Journal of Prognostics and Health Management, 2017 Data-driven condition-based maintenance (CBM) can be an effective predictive maintenance strategy for components within complex systems with unknown dynamics, nonstationary vibration signatures or a lack of historical failure data.
Ali Ashasi-Sorkhabi +3 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Experimental Validation of Motor Current Signature Analysis for a 2HP Induction Motor
Revista Facultad de Ingeniería Universidad de Antioquia, 2014 The use of stator currents signal analysis for rotating electrical machines monitoring, particularly induction motors, has developed a growing interest, as the information contained in the spectrum of the current signal can indicate the ...
Jabid E. Quiroga +2 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Cost-Optimal Maintenance Planning for Defects on Wind Turbine Blades
Energies, 2019 Due to the considerable increase in clean energy demand, there is a significant trend of increased wind turbine sizes, resulting in much higher loads on the blades.
Yi Yang, John Dalsgaard Sørensen
doaj +1 more source