Results 181 to 190 of about 1,901,647 (198)

Microstructure-Machinability correlation in heat treated AISI 1040 steel: Comparative analysis of tool life and surface roughness. [PDF]

PLoS One
Poojary UR, Hegde A, Hegde S, Mahale RS.
europepmc   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Psychometric Properties of Caregiver Contribution and Self-Efficacy Scales in Cancer. [PDF]

Nurs Health Sci
Di Nitto M, Lacarbonara F, Torino F, Bolgeo T, Damico V, Ghizzardi G, Zerulo SR, Alvaro R, Durante A, Iovino P, Vellone E.   +10 more
europepmc   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Affective Responses of Healthcare Professionals and the General Public to Health Conditions Involving Physical Dysfunction: A Cross-Sectional Web-Based Survey of Stroke, Femoral Neck Fracture, and Spinal Cord Injury. [PDF]

Healthcare (Basel)
Ochi J, Kida N.
europepmc   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Study on stability analysis of soil nail reinforced slopes under loading based on the discrete element method. [PDF]

PLoS One
Tan F, Yin G, Zhao P, Sun G, Li Z, Zhang Z.   +5 more
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Anticipatory slow potentials before auditory feedback show posterior predominance but limited condition effects in speech-in-noise. [PDF]

IBRO Neurosci Rep
Okamoto K, Hoyano K, Nomura T, Irie K, Obama N, Kodama N, Kobayashi Y.   +6 more
europepmc   +1 more source