Results 91 to 100 of about 5,841,129 (277)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Thermal System Analysis and Optimization of Large-Scale Compressed Air Energy Storage (CAES)

open access: yesEnergies, 2015
As an important solution to issues regarding peak load and renewable energy resources on grids, large-scale compressed air energy storage (CAES) power generation technology has recently become a popular research topic in the area of large-scale ...
Zhongguang Fu, Ke Lu, Yiming Zhu
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Methods for automatic condition monitoring [PDF]

open access: yes, 2017
Reliable condition monitoring is crucial to successful maintenance operations in many industrial cases but adequate manpower and expertise to conduct proper monitoring is not always available.
Karioja, Konsta
core  

Molecular dynamic simulation of bubble nucleation in a nanochannel with a groove

open access: yesAIP Advances, 2019
Molecular dynamics methods are used to investigate the effect of wall wettability and initial fluid density on the nucleation and growth of nanobubbles in a nanochannel with a groove.
Longyan Zhang, Jinliang Xu, Junpeng Lei
doaj   +1 more source

Markov chain-based mass estimation method for loose part monitoring system and its performance

open access: yesNuclear Engineering and Technology, 2017
A loose part monitoring system is used to identify unexpected loose parts in a nuclear reactor vessel or steam generator. It is still necessary for the mass estimation of loose parts, one function of a loose part monitoring system, to develop a new ...
Sung-Hwan Shin   +4 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Remote online machine condition monitoring using advanced internet, wireless and mobile communication technologies [PDF]

open access: yes, 2011
A conceptual model with wireless and mobile techniques is developed in this thesis for remote real-time condition monitoring, which is applied for monitoring, diagnosing, and controlling the working conditions of machines.
Peng, W
core  

Modeling, Validation and Analysis of the Performance of Direct Air-Cooling Condensers for Mountainous Terrain

open access: yesEnergies
Direct air-cooling systems use air instead of water as a cooling medium, so they are easily affected by meteorological and hydrological conditions. In this paper, considering the complex geographic conditions around the direct air-cooling units, Gambit ...
Xubo Lu   +4 more
doaj   +1 more source

Investigations on the Unsteady Aerodynamic Characteristics of a Horizontal-Axis Wind Turbine during Dynamic Yaw Processes

open access: yesEnergies, 2019
Wind turbines inevitably experience yawed flows, resulting in fluctuations of the angle of attack (AOA) of airfoils, which can considerably impact the aerodynamic characteristics of the turbine blades. In this paper, a horizontal-axis wind turbine (HAWT)
Xiaodong Wang   +3 more
doaj   +1 more source

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