Results 101 to 110 of about 13,304,170 (233)

Remote Condition Monitoring: A Prototype Based on Pycom Development Board FiPy and Pysense

open access: yesUK/China Emerging Technologies, 2019
Internet of Things (IoT) is not new in the market; however, they are becoming more dominant in various operations and applications. These pervasive infrastructures can collect different data in a given environment such as temperature, pressure, light ...
Andréa Voisin-Grall   +5 more
semanticscholar   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

The Heat Transfer of Microencapsulated Phase Change Material Slurry and Its Thermal Energy Storage Performance of Combined Heat and Power Generating Units

open access: yesEnergies, 2017
The application of thermal energy storage (TES) is an effective way of improving the power load regulation capability of combined heat and power (CHP) generating units.
Yonghong Guo   +4 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Thermal System Analysis and Optimization of Large-Scale Compressed Air Energy Storage (CAES)

open access: yesEnergies, 2015
As an important solution to issues regarding peak load and renewable energy resources on grids, large-scale compressed air energy storage (CAES) power generation technology has recently become a popular research topic in the area of large-scale ...
Zhongguang Fu, Ke Lu, Yiming Zhu
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Molecular dynamic simulation of bubble nucleation in a nanochannel with a groove

open access: yesAIP Advances, 2019
Molecular dynamics methods are used to investigate the effect of wall wettability and initial fluid density on the nucleation and growth of nanobubbles in a nanochannel with a groove.
Longyan Zhang, Jinliang Xu, Junpeng Lei
doaj   +1 more source

Markov chain-based mass estimation method for loose part monitoring system and its performance

open access: yesNuclear Engineering and Technology, 2017
A loose part monitoring system is used to identify unexpected loose parts in a nuclear reactor vessel or steam generator. It is still necessary for the mass estimation of loose parts, one function of a loose part monitoring system, to develop a new ...
Sung-Hwan Shin   +4 more
doaj   +1 more source

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