Results 111 to 120 of about 13,304,170 (233)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Machine learning methods for wind turbine condition monitoring: A review

Renewable Energy, 2019
This paper reviews the recent literature on machine learning (ML) models that have been used for condition monitoring in wind turbines (e.g. blade fault detection or generator temperature monitoring).
Adrian Stetco, Fateme Dinmohammadi, Xingyu Zhao, V. Robu, D. Flynn, M. Barnes, J. Keane, G. Nenadic   +7 more
semanticscholar   +1 more source

Modeling, Validation and Analysis of the Performance of Direct Air-Cooling Condensers for Mountainous Terrain

Energies
Direct air-cooling systems use air instead of water as a cooling medium, so they are easily affected by meteorological and hydrological conditions. In this paper, considering the complex geographic conditions around the direct air-cooling units, Gambit ...
Xubo Lu, Hongyi Chen, Jingyao Wang, Huimin Wei, Xiaoze Du   +4 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Investigations on the Unsteady Aerodynamic Characteristics of a Horizontal-Axis Wind Turbine during Dynamic Yaw Processes

Energies, 2019
Wind turbines inevitably experience yawed flows, resulting in fluctuations of the angle of attack (AOA) of airfoils, which can considerably impact the aerodynamic characteristics of the turbine blades. In this paper, a horizontal-axis wind turbine (HAWT)
Xiaodong Wang, Zhaoliang Ye, Shun Kang, Hui Hu   +3 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Development of an induction motor condition monitoring test rig And fault detection strategies [PDF]

, 2014
Includes bibliographical references.This thesis sets out to develop an induction motor condition monitoring test rig to experimentally simulate the common faults associated with induction motors and to develop strategies for detecting these faults that ...
Dlamini, Mpendulo
core   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source