Results 181 to 190 of about 2,975,840 (295)

Seasonal dynamic and individual determinants of <i>Amphibiocystidium</i> sp. infection in the palmate newt during the aquatic breeding season. [PDF]

Int J Parasitol Parasites Wildl
Lorrain-Soligon L, Brischoux F.
europepmc   +1 more source

Statement Exhibiting the Moral and Material Progress and Condition of India during the Year 1881-82: Eighteenth Number

, 1882
East India (Progress and Condition)
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

The Relationship of Nest-Site Selection Parameters, Timing of Breeding, Brood Size, and Nestling Body Condition With Brood Sex Ratio in the Black-Crowned Night Heron <i>Nycticorax nycticorax</i>. [PDF]

Ecol Evol
Vesali SF, Varasteh Moradi H, Amininasab SM, Pirsaraei ZA.   +3 more
europepmc   +1 more source

Statement Exhibiting the Moral and Material Progress and Condition of India during the Year 1885-86: Twenty-Second Number

, 1887
East India (Progress and Condition)
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Single-Criterion Optimisation with Consideration of Uncertainties of the Composite Multi-Layer Slabs. [PDF]

Materials (Basel)
Smela P, Miller B.
europepmc   +1 more source

Statement Exhibiting the Moral and Material Progress and Condition of India during the Year 1882-83: Nineteenth Number. Part. I

, 1885
East India (Progress and Condition)
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Stochastic Reaction Networks Within Interacting Compartments with Content-Dependent Fragmentation. [PDF]

Bull Math Biol
Anderson DF, Howells AS, La Luz DR.
europepmc   +1 more source