Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Effects of controversial contexts on opinion changes through discussion and evaluation of decisions: A group decision experiment regarding the issue of removed soil in Fukushima. [PDF]
Souma Y +7 more
europepmc +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Component analysis of a self-monitoring intervention for increasing task engagement for individuals with developmental disabilities. [PDF]
Leif E, Roscoe E, Rae L, Sheets S.
europepmc +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Exploring episodic specificity induction on divergent thinking in children. [PDF]
Tomás G, Bajo T, Marful A.
europepmc +1 more source
Neuronal correlates of spatial memory updating: c-Fos and GAD67 expression in the object-place recognition task. [PDF]
Polanczyk R +4 more
europepmc +1 more source
Item-based Parsing of Dynamic Scenes in a Combined Attentional Tracking and Working Memory Task. [PDF]
Styrkowiec PP +6 more
europepmc +1 more source
Effect of Binocularity and Depth on Static and Dynamic Accommodation Responses in Young Children. [PDF]
Vera-Diaz FA, Kerber KL.
europepmc +1 more source
The SLO Hierarchy of Pseudo-Boolean Functions and Runtime of Evolutionary Algorithms. [PDF]
Dang DC, Lehre PK.
europepmc +1 more source

