Results 61 to 70 of about 8,701,772 (260)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Domination number and neighbourhood conditions

open access: yesDiscrete Mathematics, 1999
A subset \(S\) of the vertex set of a graph \(G\) is dominating in \(G\), if each vertex of \(G\) either is in \(S\), or is adjacent to a vertex of \(S\). The minimum number of vertices of a dominating set in \(G\) is the domination number \(\gamma(G)\) of \(G\). In the paper inequalities for \(\gamma(G)\) are found, using certain numbers which concern
Chen, BF, Zhou, SM
openaire   +3 more sources

Phase transitions in the condition number distribution of Gaussian random matrices

open access: yes, 2014
We study the statistics of the condition number $\kappa=\lambda_{\mathrm{max}}/\lambda_{\mathrm{min}}$ (the ratio between largest and smallest squared singular values) of $N\times M$ Gaussian random matrices.
Castillo, Isaac Pérez   +2 more
core   +3 more sources

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

Examples of Mori dream spaces with Picard number two

open access: yes, 2014
In this note, we give a sufficient condition such that a projective variety with Picard number two is a Mori dream space.
Ito, Atsushi
core   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

Double descent in the condition number

open access: yesCoRR, 2019
In solving a system of $n$ linear equations in $d$ variables $Ax=b$, the condition number of the $n,d$ matrix $A$ measures how much errors in the data $b$ affect the solution $x$. Estimates of this type are important in many inverse problems. An example is machine learning where the key task is to estimate an underlying function from a set of ...
Tomaso A. Poggio   +2 more
openaire   +2 more sources

On the second moment of the number of crossings by a stationary Gaussian process

open access: yes, 2006
Cram\'{e}r and Leadbetter introduced in 1967 the sufficient condition \[\frac{r''(s)-r''(0)}{s}\in L^1([0,\delta],dx),\qquad \delta>0,\] to have a finite variance of the number of zeros of a centered stationary Gaussian process with twice differentiable ...
Kratz, Marie F., León, José R.
core   +3 more sources

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli   +3 more
wiley   +1 more source

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