Results 111 to 120 of about 66,452 (307)

Predicting poverty. Data mining approaches to the health and demographic surveillance system in Cuatro Santos, Nicaragua

International Journal for Equity in Health, 2019
Background In order to further identify the needed interventions for continued poverty reduction in our study area Cuatro Santos, northern Nicaragua, we aimed to elucidate what predicts poverty, measured by the Unsatisfied Basic Need index. This analysis
C. Källestål, E. Blandón Zelaya, R. Peña, W. Peréz, M. Contreras, L. Å. Persson, O. Sysoev, K. Ekholm Selling   +7 more
doaj   +1 more source

Epi-MEIF: detecting higher order epistatic interactions for complex traits using mixed effect conditional inference forests. [PDF]

Nucleic Acids Res, 2022
Saha S, Perrin L, Röder L, Brun C, Spinelli L.   +4 more
europepmc   +1 more source

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin, Qiong Li, Xuemei Xu, Yuhan Wu, Yin Zhu, Jieqiong Wu, Yuan Fang, Qiubei Chen, Shuyang Wang, Jiang Yu, Yaping Ye, Hongli Jiao   +11 more
wiley   +1 more source

SSR4 sustains Tertiary Lymphoid Structures by Regulation Quality Control of N‐linked Glycosylation During B‐cell Differentiation Into Plasmacyte in Colorectal Cancer

Advanced Science, EarlyView.
SSR4, a TRAP component induced in B cells, governs BAFFR N‐glycosylation via DDOST to sustain NF‐κB signaling, B‐cell differentiation, and TLS maturation. Its loss impairs anti‐tumor immunity, while overexpression improves antibody glycosylation and ADCC, revealing a critical regulator for cancer immunotherapy.
Wei Zhao, Youcai Zhao, Haiyang Li, Bowen Yang, Siyan Lu, Xueting Fu, Caixia Zhang, Yirong Chen, Xiaofeng Bian, Xinghua Ma, Xiaobing Yang, Bin Wang, Yuan Fang, Lulu Yang, Yelin Zhao, Shuli Zhao   +15 more
wiley   +1 more source

Racing algorithms for conditional independence inference

, 2007
In this article, we consider the computational aspects of deciding whether a conditional independence statement t is implied by a list of conditional independence statements L using the independence implication provided by the method of structural imsets.
Studený, Milan, Bouckaert, Remco R.
core   +1 more source

Sensitivity to speaker control in the online comprehension of conditional tips and promises: an eye-tracking study [PDF]

, 2013
Statements of the form if...then.... can be used to communicate conditional speech acts such as tips and promises. Conditional promises require the speaker to have perceived control over the outcome event while conditional tips do not. In an eye-tracking
Stewart, Andrew J.; id_orcid, Haigh, Matthew, Ferguson, Heather J., Ferguson, Heather, Stewart, Andrew, Stewart, Andrew J.   +5 more
core   +1 more source

Conditional inference trees in the assessment of tree mortality rates in the transitional mixed forests of Atlantic Canada. [PDF]

PLoS One, 2021
Guan H, Dong X, Yan G, Searls T, Bourque CP, Meng FR.   +5 more
europepmc   +1 more source

KRT14 Drives Basal Muscle‐Invasive Bladder Cancer Progression and Lung Metastasis by Directly Binding to and Stabilizing IGF2BP1

Advanced Science, EarlyView.
We identified a Krt14+ Igf2bp1+ bladder cancer population linked to EMT. Mechanistically, KRT14 stabilizes and transports IGF2BP1 to invasive protrusions, initiating a positive feedback loop that drives metastasis and poor outcomes. ABSTRACT Basal‐type muscle‐invasive bladder cancer (BMIBC) is characterized by aggressive metastasis and poor prognosis ...
Shirui Huang, Zhihan Zhou, Qipeng Xie, Zheng Wang, Lijiong He, Yutong Liu, Lijuan Huang, Liuxian Ye, Limeng Hu, Baokun Li, Yang Wang, Xiaohui Hua, Xuelei Liu, Yunping Zhao, Jingxia Li, Jinfei Chen, Guiying Wang, Xian Shen, Wei Chen, Chuanshu Huang   +19 more
wiley   +1 more source

Extreme Value GARCH modelling with Bayesian Inference [PDF]

Extreme value theory is widely used financial applications such as risk analysis, forecasting and pricing models. One of the major difficulties in the applications to finance and economics is that the assumption of independence of time series ...
Les Oxley, Xin Zhao, Marco Reale, Carl Scarrott   +3 more
core  

Trends and factors related to adolescent pregnancies: an incidence trend and conditional inference trees analysis of northern Nicaragua demographic surveillance data. [PDF]

BMC Pregnancy Childbirth, 2021
Pérez W, Ekholm Selling K, Zelaya Blandón E, Peña R, Contreras M, Persson LÅ, Sysoev O, Källestål C.   +7 more
europepmc   +1 more source