Results 111 to 120 of about 44,587 (300)
Brain Research BulletinEmerging evidence challenges the direct causal relationship between amyloid-β (Aβ) deposition and cognitive decline in Alzheimer's disease (AD), as exemplified in presenilin-1 and presenilin-2 conditional double knockout (cDKO) mice which exhibit no ...
Jinnan Chen +6 more
doaj +1 more source
Bayesian meta-analysis for identifying periodically expressed genes in fission yeast cell cycle
, 2010 The effort to identify genes with periodic expression during the cell cycle from genome-wide microarray time series data has been ongoing for a decade. However, the lack of rigorous modeling of periodic expression as well as the lack of a comprehensive ...
Fan, Xiaodan +2 more
core +1 more source
A guide to neuromodulation in drug‐resistant epilepsy
Epileptic Disorders, EarlyView.Abstract Neuromodulation is approved for the treatment of drug‐resistant epilepsy. It has been increasingly utilized over the past two decades with the approval of deep brain stimulation (DBS) and responsive neurostimulation (RNS) in addition to vagus nerve stimulation (VNS)—particularly in patients who are not deemed to be good resective surgical ...
Prachi Parikh +10 more
wiley +1 more source
Frequency Detection and Change Point Estimation for Time Series of Complex Oscillation
, 2020 We consider detecting the evolutionary oscillatory pattern of a signal when it is contaminated by non-stationary noises with complexly time-varying data generating mechanism. A high-dimensional dense progressive periodogram test is proposed to accurately
Guo, Yang-Guan-Jian +2 more
core
Absence seizures: Update on signaling mechanisms and networks
Epilepsia Open, EarlyView.Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley +1 more source
Earthquake and Tsunami NaTech Risk Assessment for Oil Storage Facilities
Earthquake Engineering &Structural Dynamics, EarlyView.ABSTRACT Interaction of natural and technological hazards (NaTech) events, such as tsunamis and earthquakes, can affect industrial facilities such as those featuring anchored atmospheric storage tanks. Consequences of natural events on this kind of installation may include the release of hazardous substances, which in turn can lead to industrial ...
Georgios Baltzopoulos +6 more
wiley +1 more source
eLifeThe mammalian suprachiasmatic nucleus (SCN), situated in the ventral hypothalamus, directs daily cellular and physiological rhythms across the body. The SCN clockwork is a self-sustaining transcriptional-translational feedback loop (TTFL) that in turn ...
Akanksha Bafna +5 more
doaj +1 more source
Earthquake Engineering &Structural Dynamics, EarlyView.ABSTRACT Iterative solvers are advantageous for handling nonlinear structural analysis problems. The iterative solvers often require updating the stiffness matrix, which limits their application in static and pseudo‐dynamic hybrid simulations because: (1) updating the stiffness matrix of a system involving a physical specimen is challenging; (2 ...
Junyan Xiao, Oh‐Sung Kwon, Evan Bentz
wiley +1 more source
Jump Rope Vortex in Liquid Metal Convection
, 2018 Understanding large scale circulations (LSCs) in turbulent convective systems is important for the study of stars, planets and in many industrial applications.
Aurnou, Jonathan M. +3 more
core
Energy Science &Engineering, EarlyView.Schematic diagram showing the proposed approach for EV charging/discharging. ABSTRACT The number of electric vehicles (EVs) on the road is rising as a result of recent advancements in EV technology, and EVs are important to the smart grid economy. Demand response schemes involving electric vehicles have the potential to dramatically reduce the cost of ...
F. Zonuntluanga +6 more
wiley +1 more source