Results 51 to 60 of about 39,994 (297)
Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Negative Concord (NC) constructions such as the news anchor didn’t warn nobody about the floods (meaning “the news anchor warned nobody”), in which two syntactic negations contribute a single semantic one, are stigmatized in English, while their Negative
Frances Blanchette, Cynthia Lukyanenko
doaj +1 more source
Presupposing Counterfactuality [PDF]
There is long standing agreement both among philosophers and linguists that the term ‘counterfactual conditional’ is misleading if not a misnomer. Speakers of both non-past subjunctive (or ‘would’) conditionals and past subjunctive (or ‘would have ...
Zakkou, Julia
core
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Evaluability: an alternative approach to polarity sensitivity [PDF]
Based on Brandtler (2012), this paper argues that polarity items are sensitive to evaluability, a concept that refers to the possibility of accepting or rejecting an utterance as true in a communicative exchange.
Brandtler, Johan
core +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
'Should conditionals be emergent ...': asyndetic conditionals in English and German as a Challenge to Grammaticalization Research [PDF]
The present article examines asyndetic or conjunctionless conditionals in German and English. According to Jespersen’s Model (1940), this construction arose diachronically from a paratactic discourse sequence with a polar interrogative, but more recently
Van den Nest, Daan
core +1 more source
Conditional and Conditioned Reasons
This paper is a brief reponse to some of Douglas Portmore's criticisms of our version of the agent-relative/agent-neutral distinction.In his interesting and helpful paper ‘McNaughton and Rawling on the Agent-relative/Agent-neutral Distinction’, Douglas Portmore criticizes our formalization of duties on the grounds that we have over-looked an important ...
David McNaughton, Piers Rawling
openaire +1 more source
Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron +5 more
wiley +1 more source

