Results 81 to 90 of about 48,216 (304)

Caveolin‐1 Stabilizes SERCA2 to Counteract Acute Kidney Injury via Suppression of Ca2+‐Dependent Endoplasmic Reticulum Stress in Distal Tubules

Advanced Science, EarlyView.
In AKI, initial kidney injury upregulates the expression of Cav‐1, which subsequently binds to and stabilizes SERCA2 via its scaffolding domain and through deubiquitination, thereby regulating Ca2+ homeostasis and ER stress. Conversely, Cav‐1 deficiency accelerates SERCA2 degradation, triggering Ca2+ overload and ER stress, and ultimately exacerbating ...
Yan Zhang, Xin He, Hao Huang, Rong Lu, Xin Lv, Shenglan Li, Sijue Zou, Jiawei Cheng, Yiwei Xiong, Zhenghao Deng, Qiongjing Yuan, Yanyun Xie, Ling Huang, Jiaxi Pu, Shao Liu, Qianbin Li, Jie Meng, Huixiang Yang, Lijian Tao, Zhangzhe Peng   +19 more
wiley   +1 more source

Condoms and developmental contexts in younger adolescent boys

, 2010
BACKGROUND: Condom use is a key part of sexually transmitted infection (STI) prevention for young men. Yet little is known about how younger adolescent boys initially learn about and use condoms.
Bell, David L., McBride, Kimberly R., Rosenberger, Joshua G., Ott, Mary A., Fortenberry, J. Dennis   +4 more
core   +1 more source

Formal and Informal Normative Beliefs Regarding Purchasing and Using Condoms [PDF]

, 2009
Properly using condoms is one of the most effective types of protection against HIV. To clarify the contents of normative beliefs regarding purchasing and using condoms, 390 undergraduate student volunteers were surveyed. The exploratory and confirmatory
Nakamura, Nanako, Higuchi, Masataka
core   +1 more source

A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance

Advanced Science, EarlyView.
A stable Os(III)/Os(IV) redox couple is developed to disrupt the tumor cell redox balance by concurrently catalyzing ROS generation and GSH depletion. Osmium‐treated cells exhibit multiple cell death pathways, including apoptosis, ferroptosis, and immunogenic cell death.
Wan‐Qiong Huang, Tao Huang, Yiming Hao, Gui‐Feng Huang, Yi‐Lang Yan, Xin Fang, Ying Chen, Xiao‐Long Wei, Wai‐Lun Man, Wen‐Xiu Ni   +9 more
wiley   +1 more source

Comparisons of sexual behaviors among MSM who reported always using condoms and MSM who reported not always using condoms.

, 2016
Comparisons of sexual behaviors among MSM who reported always using condoms and MSM who reported not always using condoms.
Pheak Chhoun (2208907), Carinne Brody (2208913), Sovannary Tuot (2208910), Khimuy Tith (2208916), Siyan Yi (166475), Khuondyla Pal (2208919)   +5 more
core   +1 more source

Evolução dos conhecimentos, atitudes e práticas relativas ao HIV/Aids em uma população de favela do Rio de Janeiro

Cadernos de Saúde Pública
O estudo visa acessar o estágio atual de conhecimentos, atitudes e comportamentos relativos ao HIV/Aids na população da favela da Rocinha, a qual vem sendo abrangida por um programa de controle há 6 anos. Foram entrevistados 210 moradores com idade entre
João Claudio Lara Fernandes
doaj  

Engineered Carbon Dots from a Traditional Herb Pair Orchestrate Concurrent Antioxidant and AP‐1‐Mediated Inflammation to Attenuate Renal Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study integrates two complementary traditional Chinese medicine components as precursors to synthesize bioactive AM‐AS@CDs. Compared with single‐component CDs, these dual‐component CDs exhibit enhanced antioxidant capacity and superior renoprotective effects.
Bixiao Liu, Fuying Zhu, Zhuqing Wang, Jiawen Chen, Xiaomiao Cui, Congzhong Yang, Yao Peng, Dengyuan Feng, Li Lu, Hui Wei, Xiaozhi Zhao   +10 more
wiley   +1 more source

Specimen Preparation for Condoms

, 2007
Specimen preparation techniques for Scanning Electron Microscope (SEM) imaging of condoms as reported by Rosenzweig et al revealed a variety of artifacts. The artifacts were classified as ridging, cracking and melting.
Gan Phay Fang
core   +1 more source

Targeting Golgi–STING Signaling to Reprogram Innate and Adaptive Immunity for the Treatment of Implant‐Associated Infections

Advanced Science, EarlyView.
This study presents an ultrasound‐responsive nanoplatform, CS‐BT@MZ@NEs, with a BaTiO3/Mn‐Zif‐8 core and a chondroitin sulfate coating for Golgi targeting. By leveraging neutrophil hitchhiking, it enables targeted delivery to infection sites. Under ultrasound stimulation, CS‐BT@MZ@NEs generates ROS and modulates Golgi pH to activate cGAS–STING ...
Shicheng Huo, Naifeng Zhu, Zhuocheng Lyu, Yifei Liu, Zhenjiang Xu, Chun Zhou, Yaochao Zhao, Changgui Shi   +7 more
wiley   +1 more source

Comparing condom use with different types of partners : evidence from national HIV surveys in Africa [PDF]

Based on nationally representative samples from 13 Sub-Saharan African countries, this paper reinforces and expands previous findings that condom use in general is low in this region, men report using condoms more frequently than women, and unmarried ...
Kline, Rachel, de Walque, Damien
core