Results 51 to 60 of about 9,312,615 (337)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Inverse-opal conducting polymer monoliths in microfluidic channels [PDF]

, 2012
Inverse opal monolithic flow-through structures of polyaniline (PANI) were achieved in microfluidic channels for lab-on-a-chip (LOC) applications. In order to achieve the uniformly porous monolith, polystyrene (PS) colloidal crystal (CC) templates were ...
Gorey, Brian, Morrin, Aoife, Smyth, Malcolm R., White, Blánaid   +3 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Effect of Current Density on the Corrosion Protection of Poly(o- toluidine)-coated Stainless Steel

International Journal of Electrochemical Science, 2014
This study examines the use of poly(o-toluidine) (POT) coatings for the corrosion protection of type- 304 austenitic stainless steel (SS) in natural seawater.
Aisha Ganash
doaj   +1 more source

Optical study on doped polyaniline composite films

, 2004
Localization driven by disorder has a strong influence on the conducting property of conducting polymer. A class of authors hold the opinion that disorder in the material is homogeneous and conducting polymer is disordered metal close to Anderson-Mott ...
G Li, Homes C C, J C Li, Joo J, Kittel C, Kohlman R S, Lee K, Lee K, M X Wan, Menon R, Menon R, N L Wang, P Zheng, Pinto N J, Tzamalis G, Y Z Long, Z J Chen, Zuppiroli L   +17 more
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Ru(terpy)-Based Conducting Polymer in Electrochemical Biosensing of Epinephrine

Applied Sciences, 2021
A heteroleptic [Ru(terpy)2]2+ (terpy = 2,2′:6′,2″-terpyridine) complex was electrochemically polymerized to give the corresponding metal-containing conducting polymer on gold and glassy carbon electrodes.
Francesca Meloni, Maria I. Pilo, Gavino Sanna, Nadia Spano, Antonio Zucca   +4 more
doaj   +1 more source

Inelastic electron transport in polymer nanofibers

, 2008
In this paper we present theoretical analysis of the electron transport in conducting polymers. We concentrate on the study of the effects of temperature on characteristics of the transport. We treat a conducting polymers in a metal state as a network of
Mott N. F., Natalya A. Zimbovskaya
core   +1 more source

The influence of poly (2-methoxyaniline-5-sulfonic acid) on the electrochemical and photochemical properties of a highly luminescent ruthenium complex [PDF]

, 2008
Immobilisation of a luminescent material on an electrode surface is well known to substantially modulate its photophysical and electrochemical properties.
Bard, Binran, Brune, Cameron, Cameron, Caspar, Cosnier, Dennany, Dennany, Denny, Emmet J. O’Reilly, Faulkner, Feldberg, Forster, Forster, Forster, Gordon G. Wallace, Haga, Hogan, Innis, Inzelt, Johnston, Knight, Knight, Lee, Lynn Dennany, Lyons, Masdarolomoor, Masdarolomoor, Noffsinger, Ochmanska, Peter C. Innis, Pickup, Robert J. Forster, Rubinstein, Shimizu, Tokel, Velasco, Wei, Zhang, Zhou, Zotti   +41 more
core   +1 more source