Results 81 to 90 of about 148,827 (308)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Antegrade or Retrograde Accessory Pathway Conduction: Who Dies First?

Indian Pacing and Electrophysiology Journal, 2012
A 36 year-old man with Wolff Parkinson White syndrome due to a left-sided accessory pathway (AP) was referred for catheter ablation. Whether abolition of antegrade and retrograde AP conduction during ablation therapy occurs simultaneously, is unclear. At
Claudio Hadid, MD, Darío Di Toro, MD, Sebatian Gallino, MD, Carlos Labadet, MD   +3 more
doaj   +1 more source

Loss comparison of 2 and 3-level inverter topologies

, 2010
This paper investigates semiconductor and DC-link capacitor losses in two two-level and two three-level voltage source inverters. The components of the four inverters are selected to have appropriate voltage and current ratings.
Orfanoudakis, G., Yuratich, M., Abu-Sara, M., Sharkh, S.   +3 more
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Sensorineural Hearing Loss in Otosclerosis Surgery

Acta Medica
Background: During otosclerosis surgery, operative trauma can lead to decreased bone conduction. Aims: The study aims to observe the bone conduction changes after otosclerosis operations and analyse possible factors affecting the postoperative decrease ...
Kristýna Néma, Viktor Chrobok, Jan Mejzlík, Vladimír Pavlík, Lukáš Školoudík   +4 more
doaj   +1 more source

Decay Rates of The Solution to the Cauchy Problem of the Type III Timoshenko Model Without Any Mechanical Damping

Demonstratio Mathematica, 2015
In this paper, we study the asymptotic behavior of the solutions of the one-dimensional Cauchy problem in Timoshenko system with thermal effect. The heat conduction is given by the type III theory of Green and Naghdi.
Said-Houari Belkacem
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Flat-On Secondary Crystals as Effective Blocks To Reduce Ionic Conduction Loss in Polysulfone/Poly(vinylidene fluoride) Multilayer Dielectric Films

, 2018
Recently, poly­(vinylidene fluoride) (PVDF)-based multilayer films have demonstrated good potential as high energy density, high temperature, and low loss polymer dielectrics for advanced electrical and power applications.
Huadong Huang (412116), Masafumi Fukuto (1268559), Donald E. Schuele (4803312), Masafumi Fukuto, Donald E. Schuele, Deepak Langhe (4803315), Xinyue Chen, Xinyue Chen (439708), Eric Baer (1322673), Ruipeng Li, Michael Ponting, Lei Zhu (16642), Michael Ponting (3984884), Deepak Langhe, Huadong Huang, Ruipeng Li (734290), Eric Baer, Lei Zhu   +17 more
core   +1 more source