Results 81 to 90 of about 415,138 (304)

The survival and destruction of X-ray coronae of early-type galaxies in the rich cluster environments: a case study of Abell 1367

, 2004
A new Chandra observation of the northwest region of the galaxy cluster A1367 reveals four cool galaxy coronae (0.4 - 1.0 keV) embedded in the hot intracluster medium (ICM) (5 - 6 keV).
A. Vikhlinin, C. Jones, M. Sun, Nulsen P. E. J., Pellegrini S., S. S. Murray, Takeda H., W. Forman   +7 more
core   +1 more source

Dielectric spectroscopy study of thermally-aged extruded model power cables [PDF]

, 2010
“Model” extruded power cables, having a much reduced geometry but using the same extrusion techniques and materials as full-sized cables, have been examined using dielectric spectroscopy techniques to study their thermal ageing effects.
Dissado, L. A., Dodd, S. J., Fothergill, J., Fu, M., Liu, T., Nilsson, U. H., Perrot, F.   +6 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Band engineering in dilute nitride and bismide semiconductor lasers

, 2012
Highly mismatched semiconductor alloys such as GaNAs and GaBiAs have several novel electronic properties, including a rapid reduction in energy gap with increasing x and also, for GaBiAs, a strong increase in spin orbit- splitting energy with increasing ...
Broderick, CA, Broderick, CA, O'Reilly, EP, O'Reilly, EP, Sweeney, SJ, Usman, M   +5 more
core   +1 more source

Crosslinked fluoropolymers exhibiting superior high-temperature energy density and charge-discharge efficiency [PDF]

, 2020
Superior high-temperature discharged energy densities in comparison to those of the current dielectric polymers have been demonstrated in the crosslinked ...
Ai, Ding, Gadinski, Matthew R, Han, Zhubing, Huang, Yuqi, Li, He, Ren, Lulu, Wang, Qing, Yao, Bin, Zhou, Yao   +8 more
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source