Results 91 to 100 of about 148,827 (308)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

An investigation of surficial conduction heat loss in perfectly aligned micro-wire array

open access: yes, 2019
Recently, geometrical effects in micro-/nanomaterials have gained great attention of researchers in diverse scientific and engineering fields because unique physical properties can be achieved not only by the micro-/nanosize effects of materials but also
Yoon, Jun-Bo   +9 more
core   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Effect of stapedotomy in otosclerosis patients with advanced hearing loss

open access: yesTurkish Archives of Otorhinolaryngology, 2009
Objectives:The aim of this study is to evaluate the efficiency of the surgery in otosclerosis patients with advanced hearing loss.Methods:The charts of 28 patients (30 ears) operated for otosclerosis with mean air conduction threshold greater than 70 dB ...
Fatma Çaylaklı   +3 more
doaj   +1 more source

Conduction loss Reduction Technique for a High Efficiency Phase Shift Full Bridge Converter

open access: yes, 2009
A conduction loss reduction technique for a high efficiency phase shift full bridge converter with clamp diodes is proposed in this paper. The proposed technique can be implemented simply by adding a small resonant capacitor beside the leakage inductor ...
Choi, Seong-Wook   +3 more
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Dominant symphalangism and conductive hearing loss.

open access: yesRevue de laryngologie - otologie - rhinologie, 1995
Dominant symphalangism in three generations is presented in this paper. Conductive hearing loss of a 14 year old male patient with proximal symphalangism was due to fixation of the stapes.
A, Makowski, B, Latkowski, T, Biegański
openaire   +2 more sources

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