Results 101 to 110 of about 2,900,042 (243)
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
, 2019 The transition between the insulator state and the band-conducting state is investigated by means of cyclic voltammetry in cobalt oxide porous film electrodes in phosphate-buffered solutions.
Jean-Michel Savéant (1499617) +2 more
core +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Influence of ear canal occlusion and air-conduction feedback on speech production in noise [PDF]
, 2014 Millions of workers are exposed to high noise levels on a daily basis. The primary concern for these individuals is the prevention of noise-induced hearing loss, which is typically accomplished by wearing of some type of personal hearing protector ...
Byrne, David
core
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Effect of Gradient Heat Conduction on Secondary Recrystallization of Grain-Oriented Silicon Steel
MetalsThe grain-oriented silicon steels were subjected to gradient heat conduction during high-temperature annealing by using thermal insulation cotton. The macrostructures of samples subjected to circumferential gradient heat conduction showed a “petal-like ...
Qian Gao +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Vapour sensing applications and electrical conduction mechanisms of a novel metal-polymer composite [PDF]
, 2003 A novel metal-polymer composite is presented, comprised of a micron-sized nickel powder dispersed within a silicone polymer matrix. The composite is intrinsically electrically insulating, but displays a dramatic increase in conductivity under compression,
Hands, Philip James Walton +1 more
core
Evaluation of Cochlear Function in safe type of Chronic Otitis Media
Bengal Journal of Otolaryngology and Head Neck Surgery, 2013 Objective of this article is to evaluate the correlation between the patients of safe types of chronic otitis media (COM) with their cochlear function of sensorineural hearing loss (SNHL).
Debasis Barman +5 more
doaj