Results 81 to 90 of about 2,933 (260)

Logical and linguistic features of conductive arguments in environmental media discourse

Филология: научные исследования
The subject of the study is the logical and grammatical structure of conclusions. The object of the study is conductive arguments. The authors of the article consider the implementation of such arguments in an environmental media discourse. Unlike formal logic, natural language argumentation is more often based on examples, analogies and reasoning ...
Natalya Sergeevna Barebina, Dmitrii Anatol'evich Zibrov   +1 more
openaire   +1 more source

Analysis and Computation for the Inverse Scattering Problem with Conductive Boundary Conditions

In this thesis, we consider the inverse problem of reconstructing the shape, position, and size of an unknown scattering object. We will talk about different methods used for nondestructive testing in scattering theory.
Rafael Ceja Ayala (18340938)
core   +1 more source

Convective instability of the solar corona: Why the solar wind blows

, 2016
Chapman's conductive model of the solar corona is characterized by a temperature varying as r-2/7 with heliocentric distance r. The density distribution in this non-isothermal hydrostatic model has a minimum value at 123RS, and increases with r above ...
Lemaire, J.
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Are there good and bad nationalisms?

, 1999
Writers on nationalism have continued to use the distinction between civic and cultural nationalisms; and to suggest that the former has liberal connotations while the latter is intrinsically illiberal and authoritarian.
Brown, D.
core  

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Conductivism

I propose, as an alternative to deductivism, "conductivism": the view in argumentation studies that privileges the conductive model. To this end, I first recall very briefly some versions of the deductivist thesis, and after a short review of ...
Vilanova Arias, Javier
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source