Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Studies of Intra-Chain and Inter-Chain Charge Carrier Conduction in Acid Doped Poly(3,4-ethylenedioxythiophene) Polystyrene Sulfonate Thin Films. [PDF]
Ismail AAA, Bednarski H, Marcinkowski A.
europepmc +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Memristive Behavior in Carrier Accumulation-Based Optical Modulators. [PDF]
Korneluk A, Brańko K, Stefaniuk T.
europepmc +1 more source
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Da Vinci's mischief: xylem conduits in the stems of woody plants do not furcate. [PDF]
Alemán-Sancheschúlz G +4 more
europepmc +1 more source
A challenge to claims for mycorrhizal-transmitted wound signaling. [PDF]
Blatt MR +3 more
europepmc +1 more source
Numerical and Experimental Assessment of Poly-Pyrrole Used in Spinal Cord Injuries. [PDF]
Espinoza-Garcés CA +5 more
europepmc +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Smart Cement-Based Materials Reinforced with CNT-Grafted CFs: Preparation and Performance Evaluation. [PDF]
Liu X +8 more
europepmc +1 more source

