Results 21 to 30 of about 610,412 (358)

Cone bundles [PDF]

open access: yesTransactions of the American Mathematical Society, 1977
A theory of normal bundles for locally knotted codimension two embeddings of PL manifolds is developed. The classifying space for this theory is Cappell and Shaneson’s space B R N 2 BR{N_2} .
openaire   +1 more source

An Evaluation of Initial Vancomycin Dosing in Infants, Children, and Adolescents

open access: yesInternational Journal of Pediatrics, 2011
Background. The pharmacokinetics of many medications change as we age, thus most would assume dosing strategies would adjust for these changes. The objective of this study is to evaluate the initial vancomycin dosing in three pediatric age groups based ...
Laura Broome, Tsz-Yin So
doaj   +1 more source

Generation, transcriptome profiling, and functional validation of cone-rich human retinal organoids

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance Rods and cones are photoreceptor cells with different distributions and functions in the human retina. Rods are dominant at the periphery, which is responsible for peripheral vision; cones are enriched in the macula, which is responsible for
Sangbae Kim   +14 more
semanticscholar   +1 more source

Medication Use Evaluation of Dronedarone in Comparison to Amiodarone

open access: yesINNOVATIONS in Pharmacy, 2016
Amiodarone is the most effective rhythm-control for atrial fibrillation, but produces serious potential side effects. Dronedarone was designed to eliminate amiodarone toxicities, but increased the risk of mortality in clinical trials. This medication use
Adam Corey, Nita Johnston
doaj   +1 more source

Patient Medication Use: Interpreting the Results of a Patient Medication Safety Survey by Phase I Immersion Pharmacy Students

open access: yesINNOVATIONS in Pharmacy, 2016
A medication safety survey was created during our first year pharmacy rotations in order to assess and gain insight to how safe patients are with their medications at home.
Michael Li   +2 more
doaj   +1 more source

Human foveal cone photoreceptor topography and its dependence on eye length

open access: yesbioRxiv, 2019
We provide the first measures of foveal cone density as a function of axial length in living eyes and discuss the physical and visual implications of our findings.
Yiyi Wang   +5 more
semanticscholar   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Endoscopic Repair of the Distal Biceps Tendon

open access: yesArthroscopy Techniques
Distal biceps ruptures are common orthopaedic injuries that may result in cosmetic deformity, loss of subjective flexion strength, and loss of objective supination strength if treated nonoperatively.
Steven Bokshan, M.D.
doaj   +1 more source

The Homogenization Cone: Polar Cone and Projection

open access: yesSet-Valued and Variational Analysis, 2023
Let $C$ be a closed convex subset of a real Hilbert space containing the origin, and assume that $K$ is the homogenization cone of $C$, i.e., the smallest closed convex cone containing $C \times \{1\}$. Homogenization cones play an important role in optimization as they include, for instance, the second-order/Lorentz/"ice cream" cone.
Heinz H. Bauschke   +2 more
openaire   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

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