Results 41 to 50 of about 56,714 (261)

Selective deficits of S-cone in thyroid-associated ophthalmopathy patients without clinical signs of dysthyroid optic neuropathy

Frontiers in Neuroscience, 2022
PurposeWe explored whether thyroid-associated ophthalmopathy (TAO) patients without clinical signs of dysthyroid optic neuropathy (DON) would have a selective deficit mediated by S-cone.MethodsThirty-two TAO patients without clinical signs of DON (non ...
Haochen Jin, Xi Yu, Suqi Cao, Mengting Wang, Xiaozhou Hu, Jie Ye, Weijie Liu, Mingna Xu, Wencan Wu, Yunhai Tu   +9 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Avaliação da resistência do solo à penetração em diferentes solos com a variação do teor de água Evaluation of soil resistance to penetration in different soils with varying moisture contents

Engenharia Agrícola, 2009
Com os crescimentos da população e da demanda por alimentos, novas tecnologias têm surgido visando ao aumento da produtividade e à redução nos custos de produção. Se por um lado essas tecnologias elevam a produção e reduzem os custos, por outro o tráfego
Renato L. de Assis, Gilmar D. Lazarini, Kléber P. Lanças, Alberto Cargnelutti Filho   +3 more
doaj   +1 more source

Instrumented Cone Penetrometer for Dense Layer Characterization

Sensors, 2020
Subsurface characterization is essential for a successful infrastructure design and construction. This paper demonstrates the use of an instrumented cone penetrometer (ICP) for a dense layer characterization at two sites.
Jong-Sub Lee, Yong-Hoon Byun
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Métodos probabilístico e determinístico para diagnóstico da necessidade de subsolagem de solos agrícolas Probabilistic and deterministic methods for agricultural subsoiling diagnosis

Engenharia Agrícola, 2004
Este trabalho apresenta duas metodologias para avaliar os níveis de resistência mecânica à penetração e auxiliar na tomada de decisão quanto à necessidade de se proceder à operação de subsolagem.
Gilmar da Silva, Nelson L. Cappelli, Claudio K. Umezu   +2 more
doaj   +1 more source

Investigation of Adaptive Optics Imaging Biomarkers for Detecting Pathological Changes of the Cone Mosaic in Patients with Type 1 Diabetes Mellitus. [PDF]

PLoS ONE, 2016
PURPOSE:To investigate a set of adaptive optics (AO) imaging biomarkers for the assessment of changes of the cone mosaic spatial arrangement in patients with type 1 diabetes mellitus (DM1). METHODS:16 patients with ≥20/20 visual acuity and a diagnosis of
Marco Lombardo, Mariacristina Parravano, Sebastiano Serrao, Lucia Ziccardi, Daniela Giannini, Giuseppe Lombardo   +5 more
doaj   +1 more source

Rational indexes of generators of the cone of context-free languages

Theoretical Computer Science, 1992
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source