Retinal cone photoreceptors of the deer mouse Peromyscus maniculatus: development, topography, opsin expression and spectral tuning. [PDF]
PLoS ONE, 2013 A quantitative analysis of photoreceptor properties was performed in the retina of the nocturnal deer mouse, Peromyscus maniculatus, using pigmented (wildtype) and albino animals.
Patrick Arbogast +2 more
doaj +13 more sources
A mouse model of cone photoreceptor function loss (cpfl9) with degeneration due to a mutation in Gucy2e [PDF]
Frontiers in Molecular Neuroscience, 2023 During routine screening of mouse strains and stocks by the Eye Mutant Resource at The Jackson Laboratory for genetic mouse models of human ocular disorders, we identified cpfl9, a mouse model with cone photoreceptor function loss.
Anna S. E. N. Naggert +4 more
doaj +2 more sources
The deubiquitinase Otud7b suppresses cone photoreceptor degeneration in mouse models of retinal degenerative diseases [PDF]
iScienceSummary: Primary and secondary cone photoreceptor death in retinal degenerative diseases, including age-related macular degeneration (AMD) and retinitis pigmentosa (RP), leads to severe visual impairment and blindness.
Leah Rie Varner +7 more
doaj +2 more sources
Circadian regulation of vertebrate cone photoreceptor function. [PDF]
Elife, 2021 Abstract Eukaryotes generally display a circadian rhythm as an adaption to the reoccurring day/night cycle. This is particularly true for visual physiology that is directly affected by changing light conditions.
Zang J +5 more
europepmc +4 more sources
Universality of Form: The Case of Retinal Cone Photoreceptor Mosaics [PDF]
Entropy, 2023 Cone photoreceptor cells are wavelength-sensitive neurons in the retinas of vertebrate eyes and are responsible for color vision. The spatial distribution of these nerve cells is commonly referred to as the cone photoreceptor mosaic.
Alireza Beygi
doaj +2 more sources
Modeling rod and cone photoreceptor cell survival in vivo using optical coherence tomography [PDF]
Scientific Reports, 2023 Many retinal diseases involve the loss of light-sensing photoreceptor cells (rods and cones) over time. The severity and distribution of photoreceptor loss varies widely across diseases and affected individuals, so characterizing the degree and pattern ...
S. Scott Whitmore +9 more
doaj +2 more sources
Association of shank 1A scaffolding protein with cone photoreceptor terminals in the mammalian retina. [PDF]
PLoS ONE, 2012 Photoreceptor terminals contain post-synaptic density (PSD) proteins e.g., PSD-95/PSD-93, but their role at photoreceptor synapses is not known. PSDs are generally restricted to post-synaptic boutons in central neurons and form scaffolding with multiple ...
Salvatore L Stella +7 more
doaj +6 more sources
Modeling Human Macular Cone Photoreceptor Spatial Distribution. [PDF]
Invest Ophthalmol Vis SciThe purpose of this study was to investigate the spatial distribution of human cone photoreceptors and examine cone density differences between the retinal meridians and quadrants.Using adaptive optics scanning laser ophthalmoscopy, the maculae were imaged in 17 eyes of 11 subjects with normal chorioretinal health aged 54 to 72 years.
Wang X, Hoshi S, Liu R, Zhang Y.
europepmc +3 more sources
Cone Photoreceptors in Diabetic Patients
Frontiers in Medicine, 2022 PurposeCones in diabetic patients are at risk due to metabolic and vascular changes. By imaging retinal vessel modeling at high magnification, we reduced its impact on cone distribution measurements. The retinal vessel images and retinal thickness measurements provided information about cone microenvironment.MethodsWe compared cone data in 10 diabetic ...
Ann E. Elsner +6 more
openaire +3 more sources
Journal of Innovative Optical Health Sciences, 2022 Cone photoreceptor cell identification is important for the early diagnosis of retinopathy. In this study, an object detection algorithm is used for cone cell identification in confocal adaptive optics scanning laser ophthalmoscope (AOSLO) images.
Yiwei Chen +6 more
doaj +1 more source