Effects of cyclic adenosine 3,5-monophosphate on photoreceptor disc shedding and retinomotor movement. Inhibition of rod shedding and stimulation of cone elongation. [PDF]
As a test of the hypothesis that cyclic nucleotides play a role in the regulation of retinomotor movements and disc shedding in the photoreceptor-pigment epithelial complex, we have used an in vitro eyecup preparation that sustains both disc shedding and
Besharse, J, BURNSIDE, Beth, Dunis, D
core +1 more source
Elevated expression of human bHLH factor ATOH7 accelerates cell cycle progression of progenitors and enhances production of avian retinal ganglion cells. [PDF]
The production of vertebrate retinal projection neurons, retinal ganglion cells (RGCs), is regulated by cell-intrinsic determinants and cell-to-cell signaling events.
Hashimoto, Takao +3 more
core +1 more source
A nonhuman primate model of inherited retinal disease. [PDF]
Inherited retinal degenerations are a common cause of untreatable blindness worldwide, with retinitis pigmentosa and cone dystrophy affecting approximately 1 in 3500 and 1 in 10,000 individuals, respectively.
Artemyev, Nikolai O +21 more
core
MiR-211 is essential for adult cone photoreceptor maintenance and visual function. [PDF]
MicroRNAs (miRNAs) are key post-transcriptional regulators of gene expression that play an important role in the control of fundamental biological processes in both physiological and pathological conditions.
Asteriti, Sabrina +16 more
core +3 more sources
Induction of dark-adaptive retinomotor movement (cell elongation) in teleost retinal cones by cyclic adenosine 3,5-monophosphate. [PDF]
In the teleost retina, the photoreceptors and retinal pigment epithelium (RPE) undergo extensive movements (called retinomotor movements) in response to changes in light conditions and to an endogenous circadian rhythm.
BURNSIDE, Beth +3 more
core
Automatic Detection of Cone Photoreceptors In Split Detector Adaptive Optics Scanning Light Ophthalmoscope Images [PDF]
Quantitative analysis of the cone photoreceptor mosaic in the living retina is potentially useful for early diagnosis and prognosis of many ocular diseases.
Carroll, Joseph +6 more
core +2 more sources
Purpose: Rhegmatogenous retinal detachment (RRD) can cause permanent photoreceptor damage with subsequent vision loss, even after prompt repair. Here we compared photoreceptor structure in retinal areas with varying levels of residual visual function ...
Ajay Kolli +7 more
doaj +1 more source
Retinal Architecture in \u3cem\u3eRGS9-\u3c/em\u3e and \u3cem\u3eR9AP\u3c/em\u3e-Associated Retinal Dysfunction (Bradyopsia) [PDF]
Purpose To characterize photoreceptor structure and mosaic integrity in subjects with RGS9- and R9AP-associated retinal dysfunction (bradyopsia) and compare to previous observations in other cone dysfunction disorders such as oligocone trichromacy ...
Ba-Abbad, Rola +8 more
core +1 more source
The retina visual cycle is driven by cis retinol oxidation in the outer segments of cones [PDF]
Vertebrate rod and cone photoreceptors require continuous supply of chromophore for regenerating their visual pigments after photoactivation. Cones, which mediate our daytime vision, demand a particularly rapid supply of 11-cis retinal chromophore in ...
Cornwall, M. Carter +3 more
core +2 more sources
A homozygous mutation in STK38L in dogs impairs the late phase of photoreceptor development, and is followed by photoreceptor cell death (TUNEL) and proliferation (PCNA, PHH3) events that occur independently in different cells between 7-14 weeks of age ...
Ágnes I Berta +8 more
doaj +1 more source

