Results 31 to 40 of about 42,890 (207)

Action Spectra of Zebrafish Cone Photoreceptors

PLoS ONE, 2013
Zebrafish is becoming an increasingly popular model in the field of visual neuroscience. Although the absorption spectra of its cone photopigments have been described, the cone action spectra were still unknown. In this study we report the action spectra of the four types of zebrafish cone photoreceptors, determined by measuring voltage responses upon ...
Endeman, Duco, Klaassen, Lauw J., Kamermans, Maarten   +2 more
openaire   +6 more sources

CNGA3 Mutations in Hereditary Cone Photoreceptor Disorders [PDF]

The American Journal of Human Genetics, 2001
We recently showed that mutations in the CNGA3 gene encoding the alpha-subunit of the cone photoreceptor cGMP-gated channel cause autosomal recessive complete achromatopsia linked to chromosome 2q11. We now report the results of a first comprehensive screening for CNGA3 mutations in a cohort of 258 additional independent families with hereditary cone ...
Wissinger B, Gamer D, Jagle H, Giorda R, Marx T, Mayer S, Tippmann S, Broghammer M, Jurklies B, Rosenberg T, Jacobson SG, Sener EC, Tatlipinar S, Hoyng CB, Castellan C, Bitoun P, Andreasson S, Rudolph G, Kellner U, Lorenz B, Wolff G, Verellen-Dumoulin C, Schwartz M, Cremers FPM, Apfelstedt-ylla E, Zrenner E, Salati R, Sharpe LT, Kohl S   +28 more
openaire   +5 more sources

Induction of rod versus cone photoreceptor-specific progenitors from retinal precursor cells

Stem Cell Research, 2018
During development, multipotent progenitors undergo temporally-restricted differentiation into post-mitotic retinal cells; however, the mechanisms of progenitor division that occurs during retinogenesis remain controversial.
Saeed Khalili, Brian G. Ballios, Justin Belair-Hickey, Laura Donaldson, Jeff Liu, Brenda L.K. Coles, Kenneth N. Grisé, Tahani Baakdhah, Gary D. Bader, Valerie A. Wallace, Gilbert Bernier, Molly S. Shoichet, Derek van der Kooy   +12 more
doaj   +1 more source

Disruption of the basal body protein POC1B results in autosomal-recessive cone-rod dystrophy [PDF]

, 2014
Exome sequencing revealed a homozygous missense mutation (c.317C>G [p.Arg106Pro]) in POC1B, encoding POC1 centriolar protein B, in three siblings with autosomal-recessive cone dystrophy or cone-rod dystrophy and compound-heterozygous POC1B mutations (c ...
Arts, Heleen H, Coppieters, Frauke, Cremers, Frans PM, De Baere, Elfride, de Vrieze, Erik, den Hollander, Anneke I, Hetterschijt, Lisette, Hoyng, Carel B, Kremer, Hannie, Lambertus, Stanley, Lamers, Ideke JC, Letteboer, Stef JF, Peters, Theo A, POC1B Study Group, the, Roepman, Ronald, Roosing, Susanne, van den Born, L Ingeborgh, van Wijk, Erwin   +17 more
core   +2 more sources

gdf6a is required for cone photoreceptor subtype differentiation and for the actions of tbx2b in determining rod versus cone photoreceptor fate.

PLoS ONE, 2014
Functional vision restoration is within reach via stem cell therapy, but one of the largest obstacles is the derivation of colour-sensitive cone photoreceptors that are required for high-acuity daytime vision.
Michèle G Duval, A Phillip Oel, W Ted Allison   +2 more
doaj   +1 more source

Observation of cone and rod photoreceptors in normal subjects and patients using a new generation adaptive optics scanning laser ophthalmoscope. [PDF]

, 2011
We demonstrate the capability of a new generation adaptive optics scanning laser ophthalmoscope (AOSLO) to resolve cones and rods in normal subjects, and confirm our findings by comparing cone and rod spacing with published histology measurements.
Duncan, Jacque L, Merino, David, Roorda, Austin, Tiruveedhula, Pavan   +3 more
core   +3 more sources

Optoretinography of individual human cone photoreceptors

Optics Express, 2020
Photoreceptors mediate the first step of vision, transducing light and passing signals to retinal neurons that ultimately send signals along the optic nerve to the brain. A functional deficiency in the photoreceptors, due to either congenital or acquired disease, can significantly affect an individual’s sight and quality of life.
Robert F Cooper, David H Brainard, Jessica I. W. Morgan   +2 more
openaire   +2 more sources

Loss of Class III Phosphoinositide 3-Kinase Vps34 Results in Cone Degeneration

Biology, 2020
The major pathway for the production of the low-abundance membrane lipid phosphatidylinositol 3-phosphate (PI(3)P) synthesis is catalyzed by class III phosphoinositide 3-kinase (PI3K) Vps34.
Ammaji Rajala, Feng He, Robert E. Anderson, Theodore G. Wensel, Raju V. S. Rajala   +4 more
doaj   +1 more source

Functional identification of an opsin kinase underlying inactivation of the pineal bistable opsin parapinopsin in zebrafish

Zoological Letters, 2021
In the pineal organ of zebrafish larvae, the bistable opsin parapinopsin alone generates color opponency between UV and visible light. Our previous study suggested that dark inactivation of the parapinopsin photoproduct, which activates G-proteins, is ...
Baoguo Shen, Seiji Wada, Haruka Nishioka, Takashi Nagata, Emi Kawano-Yamashita, Mitsumasa Koyanagi, Akihisa Terakita   +6 more
doaj   +1 more source

Bat Eyes Have Ultraviolet-Sensitive Cone Photoreceptors [PDF]

PLoS ONE, 2009
Mammalian retinae have rod photoreceptors for night vision and cone photoreceptors for daylight and colour vision. For colour discrimination, most mammals possess two cone populations with two visual pigments (opsins) that have absorption maxima at short wavelengths (blue or ultraviolet light) and long wavelengths (green or red light). Microchiropteran
Müller, Brigitte, Glösmann, Martin, Peichl, Leo, Knop, Gabriel C., Hagemann, Cornelia, Ammermüller, Josef   +5 more
openaire   +6 more sources