Results 51 to 60 of about 7,507,069 (350)

How Should Happiness Guide Policy? Why Gross National Happiness is not opposed to Democracy [PDF]

open access: yes, 2005
Gross National Happiness (GNH) as a political program carries with it the ambition to make a difference to real policy decisions. Whatever the precise understanding of GNH, it was al-ways intended to be more than a purely theoretical concept and to make ...
Hirata, Johannes
core  

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

A report on the first virtual PLDI conference [PDF]

open access: yesarXiv, 2020
This is a report on the PLDI 2020 conference, for which I was General Chair, which was held virtually for the first time as a result of the COVID-19 pandemic. The report contains: my personal reflections on the positive and negative aspects of the event; a description of the format of the event and associated logistical details; and data (with some ...
arxiv  

Abstract Book of the 31° Congresso Nazionale SIGOT - Genova, 8-9 giugno 2017

open access: yesGeriatric Care, 2017
Book of the 31° Congresso Nazionale SIGOT - Genova, 8-9 giugno 2017.
Editor-in-Chief: Alberto Pilotto
doaj   +1 more source

Sleuths and Spies: the rise of the 'Everywoman' in detective and thriller fiction of the 1920s [PDF]

open access: yes, 2013
The 1920s, frequently referred to as the ‘Roaring Twenties’ or the ‘Jazz Age’, are often associated with opulent lifestyles and the emergence of striking fashion and furniture trends.
Bydder, Jillene, Franks, Rachel
core   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Make Scientific Conferences More Inclusive by Increasing Transparency in Speaker Selection [PDF]

open access: yesarXiv, 2021
Scientific conferences play an important part in every scientists career. Here, I suggest an approach that can mitigate biases and help make scientific conferences more inclusive for everybody by increasing the transparency in speaker selection.
arxiv  

High performance workplaces and skill development: Updating the map of the territory [PDF]

open access: yes, 2006
The impact of High Performance Workplace Systems (HPWS) on workers and unions is a contentious area for debate in the fields of industrial relations and social science in general. Proponents of HPWS claim that one of the benefits for workers is that they
Cochrane, William   +4 more
core   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

The Impact of the Virtualization of Scholarly Conferences on the Gender Structure of Conference Contributors [PDF]

open access: yes
This study investigates whether the virtualization of academic conferences in the wake of the COVID-19 pandemic changed the gender structure of conference participants. We explored this question utilizing authorship data from the Web of Science Conference Proceedings Citation Index for 180 conferences in 30 conference series held between 2017 and 2023.
arxiv   +1 more source

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