Results 121 to 130 of about 5,234,127 (383)

Simple Confidence Intervals for MCMC Without CLTs [PDF]

arXiv, 2018
This short note argues that 95% confidence intervals for MCMC estimates can be obtained even without establishing a CLT, by multiplying their widths by 2.3.
arxiv  

Confidence Interval Estimation Tasks and the Economics of Overconfidence [PDF]

Experiments in psychology, where subjects estimate confidence intervals to a series of factual questions, have shown that individuals report far too narrow intervals. This has been interpreted as evidence of overconfidence in the preciseness of knowledge,
Cesarini, David, Johannesson, Magnus, Sandewall, Örjan   +2 more
core  

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Robust misinterpretation of confidence intervals

Psychonomic Bulletin & Review, 2014
Null hypothesis significance testing (NHST) is undoubtedly the most common inferential technique used to justify claims in the social sciences. However, even staunch defenders of NHST agree that its outcomes are often misinterpreted. Confidence intervals (CIs) have frequently been proposed as a more useful alternative to NHST, and their use is strongly
Hoekstra, R., Morey, R.D., Rouder, J.N., Wagenmakers, E.-J.   +3 more
openaire   +8 more sources

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

General concepts in biostatistics and clinical epidemiology: Random error and systematic error

Medwave, 2019
Resumen La investigación biomédica, particularmente la que involucra a seres humanos, está siempre sometida a fuentes de error que deben ser reconocidas.
Felipe Barraza, Marcelo Arancibia, Eva Madrid, Cristian Papuzinski   +3 more
doaj   +1 more source

What is the Usefulness of Frequentist Confidence Intervals? [PDF]

arXiv, 2000
The following questions are discussed: ``Why confidence intervals are a hot topic?''; ``Are confidence intervals objective?''; ``What is the usefulness of coverage?''; ``How to obtain useful information from experiment?''; ``The confidence level must be chosen independently from the knowledge of the data?''.
arxiv  

Simultaneous Confidence Interval Estimation [PDF]

, 1953
Sasanka Roy, R. C. Bose
openalex   +1 more source

A Note on Confidence Interval Estimation and Margin of Error

, 2010
Confidence interval estimation is a fundamental technique in statistical inference. Margin of error is used to delimit the error in estimation. Dispelling misinterpretations that teachers and students give to these terms is important.
D. Gilliland, Vincent F. Melfi
semanticscholar   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source