Results 81 to 90 of about 2,097,293 (339)
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Journal of Probability and Statistics, 2015 Model averaging is a technique used to account for model uncertainty, in both Bayesian and frequentist multimodel inferences. In this paper, we compare the performance of model-averaged Bayesian credible intervals and frequentist confidence intervals ...
Daniel Turek
doaj +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
On a linear method in bootstrap confidence intervals
Statistica, 2007 A linear method for the construction of asymptotic bootstrap confidence intervals is proposed. We approximate asymptotically pivotal and non-pivotal quantities, which are smooth functions of means of n independent and identically distributed random ...
Andrea Pallini
doaj +1 more source
Varieties of Confidence Intervals
Advances in Cognitive Psychology, 2017 Error bars are useful to understand data and their interrelations. Here, it is shown that confidence intervals of the mean (CI M s) can be adjusted based on whether the objective is to highlight differences between measures or not and based on the experimental design (within- or between-group designs). Confidence intervals (CIs) can also be adjusted to
openaire +2 more sources
Confidence intervals for average success probabilities [PDF]
, 2014 We provide Buehler-optimal one-sided and some valid two-sided confidence intervals for the average success probability of a possibly inhomogeneous fixed length Bernoulli chain, based on the number of observed successes.
Mattner, Lutz, Tasto, Christoph
core
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
Redefining the Confidence Interval
Human and Ecological Risk Assessment: An International Journal, 2005 The confidence interval, its close cousin the p-value, and other statistical summaries of data are widely used in science, including the occupational and environmental health sciences, but they are almost as widely misused. My purpose here is to review some basic matters that should be covered in every introductory statistics course, but are generally ...
openaire +2 more sources
Aging and Cancer, EarlyView.This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst +4 more
wiley +1 more source
Corrected confidence intervals for secondary parameters following sequential tests
, 2006 Corrected confidence intervals are developed for the mean of the second component of a bivariate normal process when the first component is being monitored sequentially.
Coad, D. S., Weng, R. C.
core +1 more source