Results 111 to 120 of about 9,151,209 (331)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Constructing networks for comparison of collagen types
Journal of Integrative BioinformaticsCollagens are structural proteins that are predominantly found in the extracellular matrix of multicellular animals, where they are mainly responsible for the stability and structural integrity of various tissues.
Wesp Valentin +4 more
doaj +1 more source
Robust Markov Decision Processes [PDF]
Markov decision processes (MDPs) are powerful tools for decision making in uncertain dynamic environments. However, the solutions of MDPs are of limited practical use due to their sensitivity to distributional model parameters, which are typically ...
Berç Rustem +2 more
core
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
HeliyonThe objective of the current study was to assess the levels of access of agricultural agents in the Sidama Region to agriculture-specific information from researchers and the media and its effect on their confidence in communicating with farmers.
Hailemesekel Zewedie Gebeyehu +1 more
doaj +1 more source
Consumer confidence and consumers' preferences for infant formulas in China
Journal of Integrative Agriculture, 2019 A series of safety incidents related to domestically-produced infant formulas (DIFs) almost destroyed Chinese consumer confidence in domestic dairy products. Understanding consumer confidence and its effect on consumption behavior is important to restore
Sai-wei LI +3 more
doaj +1 more source
On the local dynamics of polynomial difference equations with fading stochastic perturbations [PDF]
, 2010 We examine the stability-instability behaviour of a polynomial difference equa- tion with state-independent, asymptotically fading stochastic perturbations. We find that the set of initial values can be partitioned into a stability region, an instability
Appleby, John A.D. +3 more
core
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Path Forecast Evaluation [PDF]
A path forecast refers to the sequence of forecasts 1 to H periods into the future. A summary of the range of possible paths the predicted variable may follow for a given confidence level requires construction of simultaneous confidence regions that ...
Massimiliano Marcellino, Òscar Jordà
core +3 more sources
Calibrating and Visualizing Some Bootstrap Confidence Regions
AxiomsWhen the bootstrap sample size is moderate, bootstrap confidence regions tend to have undercoverage. Improving the coverage is known as calibrating the confidence region. Consider testing H0:θ=θ0 versus H1:θ≠θ0.
Welagedara Arachchilage Dhanushka M. Welagedara +1 more
doaj +1 more source