Results 41 to 50 of about 774,398 (260)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Product quality evaluation by confidence intervals of process yield index

open access: yesScientific Reports, 2022
Statistical techniques have a beneficial effect on measuring process variability, analyzing the variability concerning product requirements, and eliminating the variability in product manufacturing.
Kuen-Suan Chen   +2 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Empirical likelihood confidence regions of the parameters in a partially single-index varying-coefficient model

open access: yesOpen Mathematics, 2019
In this paper, we investigate a partially single-index varying-coefficient model, and suggest two empirical log-likelihood ratio statistics for the unknown parameters in the model.
Xiang Xing, Liu Wanrong
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

An Efficient Construction of Confidence Regions via Swarm Intelligence and Its Application in Target Localization

open access: yesIEEE Access, 2018
It is essential to enhance the speed and accuracy of the localization process to gain the robustness and instantaneous properties and to adapt from the practical environment of a confidence band.
Frank Po-Chen Lin   +1 more
doaj   +1 more source

Minimum Area Confidence Region for Weibull Distribution Based on Records

open access: yesRevstat Statistical Journal, 2021
Record values are commonly seen in real life applications, and many important studies on record values relate to Weibull distributions. Based on record values, we establish the minimum area confidence region for the two-parameter Weibull distribution ...
Junmei Zhou , Fen Jiang , Jin Zhang
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Robust confidence regions for multinomial probabilities

open access: yes, 2015
Generally, confidence regions for the probabilities of a multinomial population are constructed based on the Pearson chi(2) statistic. Morales et al. (Bootstrap confidence regions in multinomial sampling. Appl Math Comput.
Basu, Ayanendranath, ALIN, AYLİN
core   +1 more source

Confidence in COVID-19 vaccine effectiveness and safety and its effect on vaccine uptake in Tanzania: A community-based cross-sectional study

open access: yesHuman Vaccines & Immunotherapeutics, 2023
COVID-19 is a major public health threat associated with increased disease burden, mortality, and economic loss to countries and communities. Safe and efficacious COVID-19 vaccines are key in halting and reversing the pandemic. Low confidence in vaccines
Monica Mtei   +19 more
doaj   +1 more source

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