Results 61 to 70 of about 774,398 (260)

Cooperative Position Aware Mobility Pattern of AUVs for Avoiding Void Zones in Underwater WSNs

open access: yesSensors, 2017
In this paper, we propose two schemes; position-aware mobility pattern (PAMP) and cooperative PAMP (Co PAMP). The first one is an optimization scheme that avoids void hole occurrence and minimizes the uncertainty in the position estimation of glider’s ...
Nadeem Javaid   +6 more
doaj   +1 more source

An assessment of the public confidence in governance institutions in India: Empirical evidence using IHDS survey

open access: yesJournal of Government and Economics, 2023
Using two rounds of the Indian Human Development Survey (2004–05 & 2011–12), this study evaluates levels of household confidence in the governance institutions across Indian states. The observed broad pattern conveys that although there is a marginal
Hrushikesh Mallick   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

ON THE CONSTRUCTION OF BOUNDS CONFIDENCE REGIONS

open access: yes, 2003
We modify the procedure for constructing exact bounds confidence regions introduced by Dufour (1990, Econometrica 58, 475-494) so as to drop the requirement that the confidence regions for the nuisance parameters are marginal with respect to the ...
Kemp, Gordon CR
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Separating the brain regions involved in recollection and familiarity in recognition memory [PDF]

open access: yes, 2005
The neural substrates of recognition memory retrieval were examined in a functional magnetic resonance imaging study designed to separate activity related to recollection from that related to continuous variations in familiarity.
Rugg, M. D.   +7 more
core  

Confidence Intervals and Regions for the Generalized Inverted Exponential Distribution Based on Progressively Censored and Upper Records Data

open access: yesRevstat Statistical Journal, 2019
In this paper, we study the estimation problems for the generalized inverted exponential distribution based on progressively type-II censored order statistics and record values.
Ismail Kınacı   +2 more
doaj   +1 more source

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