Results 51 to 60 of about 1,986,171 (336)

Confidence in COVID-19 vaccine effectiveness and safety and its effect on vaccine uptake in Tanzania: A community-based cross-sectional study

open access: yesHuman Vaccines & Immunotherapeutics, 2023
COVID-19 is a major public health threat associated with increased disease burden, mortality, and economic loss to countries and communities. Safe and efficacious COVID-19 vaccines are key in halting and reversing the pandemic. Low confidence in vaccines
Monica Mtei   +19 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

A stochastic approach to estimate distribution grid state with confidence regions

open access: yesInternational Journal of Electrical Power & Energy Systems
Measurement equipment located in electrical distribution grids, as power-quality measurement devices, substation meters, or customer smart meters do not provide phasor measurements due to the lack of high resolution time synchronization.
Rasmus L. Olsen   +4 more
doaj   +1 more source

How confidence in health care systems affects mobility and compliance during the COVID-19 pandemic.

open access: yesPLoS ONE, 2020
Confidence in the health care system implies an expectation that sufficient and appropriate treatments will be provided if needed. The COVID-19 public health crisis is a significant, global, and (mostly) simultaneous test of the behavioral implications ...
Ho Fai Chan   +7 more
doaj   +1 more source

Smoothed and Iterated Bootstrap Confidence Regions for Parameter Vectors [PDF]

open access: yes, 2013
The construction of confidence regions for parameter vectors is a difficult problem in the nonparametric setting, particularly when the sample size is not large.
Ghosh, Santu, Polansky, Alan M.
core  

Honest confidence regions and optimality in high-dimensional precision matrix estimation

open access: yes, 2016
We propose methodology for estimation of sparse precision matrices and statistical inference for their low-dimensional parameters in a high-dimensional setting where the number of parameters $p$ can be much larger than the sample size.
Janková, Jana, van de Geer, Sara
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Identification of recurrent regions of copy-number variants across multiple individuals

open access: yesBMC Bioinformatics, 2010
Background Algorithms and software for CNV detection have been developed, but they detect the CNV regions sample-by-sample with individual-specific breakpoints, while common CNV regions are likely to occur at the same genomic locations across different ...
Calza Stefano   +5 more
doaj   +1 more source

Confidence Regions in Multivariate Calibration

open access: yesThe Annals of Statistics, 1988
The multivariate calibration problem is considered, in which a sample of n observations on vectors \(\xi_{(i)}\) (of ``true values'') and \(Y_{(i)}\) (of less accurate but more easily obtained values) are to be used to estimate the unknown \(\xi\) corresponding to a future Y.
openaire   +3 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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