Results 81 to 90 of about 751,928 (265)
BMC Genetics, 2012 Background The traditional strategy to map QTL is to use linkage analysis employing a limited number of markers. These analyses report wide QTL confidence intervals, making very difficult to identify the gene and polymorphisms underlying the QTL effects.
Fernández Ana I +9 more
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From Conformal Predictions to Confidence Regions
CoRRConformal prediction methodologies have significantly advanced the quantification of uncertainties in predictive models. Yet, the construction of confidence regions for model parameters presents a notable challenge, often necessitating stringent assumptions regarding data distribution or merely providing asymptotic guarantees.
Charles Guille-Escuret, Eugène Ndiaye
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Nonparametric regression, confidence regions and regularization
The Annals of Statistics, 2009 In this paper we offer a unified approach to the problem of nonparametric regression on the unit interval. It is based on a universal, honest and non-asymptotic confidence region which is defined by a set of linear inequalities involving the values of the functions at the design points.
Davies, P. L., Kovac, A., Meise, M.
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Adjusted empirical likelihood confidence regions for stationary autoregressive models
四川大学学报. 自然科学版Autoregressive models are widely used in diverse fields such as economics and information science.The statistical inference problem of autoregressive models is an important research topic in statistics.This paper aims at the adjusted empirical likelihood
HOU Meng-Zhe +2 more
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Frontiers in Public HealthBackgroundUniversal health coverage (UHC) aims to ensure that all people can access quality health services without financial hardship, and thereby improve health outcomes.
Zhaoxi Wang, Kairan Zhang
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Distribution of Toxoplasma gondii among cattle in certain regions of Ukraine
Ukrainian Journal of Veterinary Sciences, 2022 Toxoplasma gondii is the agent of toxoplasmosis, which is common to both humans and cattle. That is why the goal of work was to study the spreading of the agent of toxoplasmosis among cattle in certain regions of Ukraine, which in turn will make it ...
Vladyslava Storozhuk +6 more
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Co-Saliency Detection for RGBD Images Based on Effective Propagation Mechanism
IEEE Access, 2019 Given a group of images, co-saliency detection aims at highlighting the common and salient foreground regions. To optimally explore the complementary information among images, we propose an effective propagation mechanism for RGBD images.
Zhigang Jin, Jingkun Li, Dong Li
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source