Results 91 to 100 of about 3,449,680 (270)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Effect of Nanosecond Pulsed Dielectric Barrier Discharge Plasma Actuation on the Longitudinal Characteristics of Flying-Wing Aircraft

open access: yes气体物理
To improve the longitudinal aerodynamic characteristics of flying-wing configuration aircraft, a numerical simulation study on flow control using nanosecond pulse dielectric barrier discharge (NSDBD) plasma was conducted.
Fengling GUO   +4 more
doaj   +1 more source

Heat Transfer Enhancement using Combined Microchannel with Vertical Rectangular Micro Fins

open access: yesNigerian Journal of Technological Development, 2023
This paper focuses on the numerical optimisation of a combined hybrid microchannel heat sink with rectangular solid fins. The axial length and volume are fixed, and external structure is allowed to vary. The simulation was performed on an elemental unit
N. Y. Godi
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Study on the Aeroelastic Characteristics of a Large-Span Joined-Wing Solar-Powered UAV

open access: yesAerospace
When a joined-wing configuration is applied to the design of solar-powered UAVs, the increasing span amplifies aeroelastic effects, while structure complexity poses greater challenges to computational effectiveness during the conceptual design phase ...
Xinyu Tong   +5 more
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Selecting Focal Songbird Species for Biodiversity Conservation Assessment: Response to Forest Cover Amount and Configuration

open access: yesAvian Conservation and Ecology, 2007
Conservation of biodiversity is now a firmly entrenched objective of sustainable forest management, and emulating natural disturbance has been widely adopted as a conservation strategy. Yet the foundation for this approach is still very much a hypothesis
Robert S. Rempel
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A novel trajectories optimizing method for dynamic soaring based on deep reinforcement learning

open access: yesDefence Technology
Dynamic soaring, inspired by the wind-riding flight of birds such as albatrosses, is a biomimetic technique which leverages wind fields to enhance the endurance of unmanned aerial vehicles (UAVs).
Wanyong Zou   +4 more
doaj   +1 more source

Configuration Analysis of Influencing Factors of Technical Efficiency Based on DEA and fsQCA: Evidence from China’s Medical and Health Institutions

open access: yesRisk Management and Healthcare Policy, 2021
Zhiguang Li,1 Wanying Zhang,1 Aijie Kong,1 Zhiyuan Ding,1 Hua Wei,1 Yige Guo2 1School of Economics and Management, Anhui University of Chinese Medicine, Hefei, Anhui, People’s Republic of China; 2King’s Business School, King’s College ...
Li Z   +5 more
doaj  

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