Results 91 to 100 of about 474,935 (329)

Monodromy relations from twisted homology

open access: yesJournal of High Energy Physics, 2019
We reformulate the monodromy relations of open-string scattering amplitudes as boundary terms of twisted homologies on the configuration spaces of Riemann surfaces of arbitrary genus.
Eduardo Casali   +2 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

KAM theory in configuration space

open access: yesCommentarii Mathematici Helvetici, 1989
A Hamiltonian system is considered in the 2n-dimensional space and the Hamiltonian is supposed to be periodic in the first n coordinates, i.e. the system is defined on \(T^ n\times R^ n\) where \(T^ n\) is the n- dimensional torus. The problem is transformed into a variational problem whose Euler-Lagrange equation gives rise to a nonlinear partial ...
Zehnder, Eduard, Salamon, Dietmar
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Geostrategy of Economic Spaces: Innovation and Change in Latin America Territorial Administration

open access: yesJournal of Technology Management & Innovation, 2008
In this essay we analyze the geostrategy of economic spaces in the sphere of new links in the global economy, placing Latin America in the scenario of the new world order.
Euripedes Falcão Vieira   +1 more
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

PBDW State Estimation: Noisy Observations; Configuration-Adaptive Background Spaces; Physical Interpretations

open access: yesESAIM: Proceedings and Surveys, 2015
We provide extended analyses and interpretations of the parametrized-background data-weak (PBDW) formulation, a real-time in situ data assimilation framework for physical systems modeled by parametrized partial differential equations.
Maday Yvon   +3 more
doaj   +1 more source

Assessing the Distribution of Urban Green Spaces and its Anisotropic Cooling Distance on Urban Heat Island Pattern in Baotou, China

open access: yesISPRS International Journal of Geo-Information, 2016
An essential part of urban natural systems, urban green spaces play a crucial role in mitigating the urban heat island effect (UHI). The UHI effect refers to the phenomenon where the temperature within a city is higher than that of the surrounding rural ...
Tongliga Bao   +4 more
doaj   +1 more source

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