Results 201 to 210 of about 16,352 (264)

Failure mechanisms and energy evolution of jointed rock-like materials under triaxial compression: experimental and numerical simulation study. [PDF]

Sci Rep
Dou H, Chen C, Li Z, Li J, Zhu L, Wang C.   +5 more
europepmc   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Sand Production Mechanisms in Sandstone Gas Reservoirs during Cyclic Injection-Production with Variable Water Saturation. [PDF]

ACS Omega
Tang X, Yang B, Hu J, Zhang Y, Cai Y, Lu J.   +5 more
europepmc   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

The influence of stress path and flaw morphology on the failure mechanism and mechanical properties of rock masses. [PDF]

PLoS One
Wu N, Gan Y, Hu J, Sun R, Zeng H.
europepmc   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Mesoscale Mechanisms Governing the Shear Strength of Lunar Regolith: Effects of Low Confining Stress and Irregular Particle Morphology. [PDF]

Materials (Basel)
Chen J, Li R, Ji Y, Mo P.
europepmc   +1 more source

Seepage characteristics of fractured sandstone under deep high-confined water and mining-induced stress. [PDF]

Sci Rep
Tu H, Wu R, Jia S, Fang S, Zhang C.
europepmc   +1 more source

Study on rock energy and microscopic failure under different stress states. [PDF]

Sci Rep
Xie L, Li B, Sun J, Jin J, Zhang J.
europepmc   +1 more source

Study on the anisotropic characteristics of mechanical properties and energy evolution in layered phyllite. [PDF]

PLoS One
Chen L, Xi B, Zhao N, Dong Y, He S, Liu K, Gao P, Xie J.   +7 more
europepmc   +1 more source