Results 191 to 200 of about 23,904 (309)

Residual strength of granitic rocks: interplay between GSI and confining pressure. [PDF]

Sci Rep
Narimani S, Davarpanah SM, Török Á, Vásárhelyi B.   +3 more
europepmc   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Energy evolution and damage characteristics of coal rock under graded cyclic loading and unloading with confining pressure. [PDF]

Sci Rep
Chen Z, Dang S, Wang C, Shen M, Wei T, Cao Q.   +5 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Study on Acoustic Emission <i>b</i>‑Value Characteristics in Hydraulically Fractured Shale Fracture Propagation under High Confining Pressure Conditions. [PDF]

ACS Omega
Zhao H, Sun W, Liang B, Yang Y, Wang C, Liu Q, Liao B, Bu Y, Zhao Y, Gao Y, Wu X, Zeng X.   +11 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Strength of artificially frozen sand with low confining pressure under a three-dimensional stress path. [PDF]

Sci Rep
Yao Z, Xu X, Liu S.
europepmc   +1 more source

Creep and permeability evolution behavior of red sandstone containing a single fissure under a confining pressure of 30 MPa. [PDF]

Sci Rep, 2020
Yang SQ, Hu B.
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Study on a Creep Constitutive Model of Phyllite Considering the Coupling Factors of Bedding, Confining Pressure, and Water Saturation. [PDF]

ACS Omega
Wu Y, Hu J, Yang D, Wen G.
europepmc   +1 more source