Results 81 to 90 of about 131,723 (308)

Experimental investigation on shock mechanical properties of red sandstone under preloaded 3D static stresses [PDF]

, 2015
Triaxial impact mechanical performance experiment was performed to study the mechanical properties of red sandstone subjected to three-dimensional (3D) coupled static and dynamic loads, i.e., three confining pressures (0, 5, and 10 MPa) and three axial ...
Deke, Liu, Kegang, Li, Shoujian, Peng, Xianglong, Li, Yong, Niu   +4 more
core   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Yielding and hardening of flexible fiber packings during triaxial compression

, 2019
This paper examines the mechanical response of flexible fiber packings subject to triaxial compression. Short fibers yield in a manner similar to typical granular materials in which the deviatoric stress remains nearly constant with increasing strain ...
Curtis, Jennifer, Guo, Yu, Jin, Hanhui, Li, Yanjie, Liu, Qingzhao, Wassgren, Carl, Xu, Dandan   +6 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Influence of Confining Pressure Unloading Rate on the Strength Characteristics and Fracture Process of Granite Using Lab Tests

Advances in Materials Science and Engineering, 2021
In order to study the mechanical behaviors and fracture process properties of granite under confining pressure unloading with constant axial pressure, RMT-150B rock mechanics test system and acoustic emission detector were used to study the mechanical ...
Jiaqi Guo, Pengfei Liu, Junqi Fan, Xiaoyan Shi, Xin Huang   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Energy characteristics of saturated Jurassic sandstone in western China under different stress paths

Deep Underground Science and Engineering
To study the energy evolution and failure characteristics of saturated sandstone under unloading conditions, rock unloading tests under different stress paths were conducted.
Yi Yang, Jian Lin, Yun Wu, Shilong Peng, Wanhang Shao, Lining Yang   +5 more
doaj   +1 more source

Stress transmission in wet granular materials

, 2006
We analyze stress transmission in wet granular media in the pendular state by means of three-dimensional molecular dynamics simulations. We show that the tensile action of capillary bonds induces a self-stressed particle network organized in two ...
Bocquet, Calvetti, Castellanos, Castellanos, Cates, Christoffersen, Coppersmith, Corwin, Cundall, Dauchot, Dippel, Erle, F. Radjaı, Fillot, Fournier, Halsey, Hecke, Herminghaus, Hornbaker, Jaeger, Jean, Knight, Kuhn, Lian, Lian, M. S. El Youssoufi, Majmudar, Mikami, Moreau, Mueth, Oda, Radja\"ı, Radja\"ı, Radja\"ı, Radja\"ı, Radja\"ı, Richefeu, Rothenburg, Roux, Schäfer, Soulié, Staron, Staron, Troadec, V. Richefeu, Willett, Yang, Youssoufi   +47 more
core   +3 more sources

Discrete element modelling of a flexible membrane for triaxial testing of granular material at high pressures [PDF]

, 2012
The discrete element method (DEM) has been used to simulate triaxial tests on a bonded material at high pressures. A key feature of the model is the use of a flexible membrane that allows the correct volumetric deformation and the true failure mode to ...
de Bono, John P., McDowell, Glenn R., Wanatowski, Dariusz   +2 more
core   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source