Results 191 to 200 of about 410,640 (327)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Portuguese Workers of Private Institutions of Social Solidarity and Affective Job Satisfaction: An Exploratory and Confirmatory Factor Analysis. [PDF]

Eur J Investig Health Psychol Educ
Silva S, Pocinho R, Rodriguez Conde MJ, Topa G, Fernández Muñoz JJ.   +4 more
europepmc   +1 more source

Testing the Measurement Invariance of Political Trust across the Globe. A Multiple Group Confirmatory Factor Analysis

, 2018
Wiebke Breustedt
openalex   +2 more sources

Sporting, financial and stock market performance in English football: an empirical analysis of structural relationships [PDF]

This paper uses structural equation modeling to examine the linkages between financial performance, sporting performance and stock market performance for English football clubs over the period from 1995 to 2007.
Antonio Samagaio, Eduardo Couto, Jorge Caiado   +2 more
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Assessing internal construct validity of DAPSA and DAPSA28 in psoriatic arthritis: a European observational study using confirmatory factor analysis and additional psychometric testing. [PDF]

RMD Open
Jørgensen JB, Christensen KB, Michelsen B, Loft AG, Horskjær Rasmussen S, Heberg J, Hetland ML, Zavada J, Pavelka K, Iannone F, Conti F, Borges J, Codreanu C, Mogosan C, Glintborg B, Ciurea A, Nissen MJ, Nordström D, Kuusalo L, Laas K, Vorobjov S, Gudbjornsson B, Love TJ, Østergaard M, Ørnbjerg LM.   +24 more
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Construct Validity of the Staff Resource Adequacy Questionnaire for Healthcare Professionals (SRAQ-HP): An Exploratory and Confirmatory Factor Analysis from Latvia. [PDF]

Nurs Rep
Cerela-Boltunova O, Millere I, Trups-Kalne I.   +2 more
europepmc   +1 more source

Development Instruments Through Confirmatory Factor Analysis (CFA) in Appropriate Intensity Assessment

, 2017
Ari Saptono
openalex   +1 more source

Effort and reward imbalance factors motivating Namibian professional nurses to participate in continuous professional development: A confirmatory factor analysis [PDF]

, 2020
Tekla S.N. Mbidi, Anneleen Damons
openalex   +1 more source