Results 91 to 100 of about 7,934,450 (360)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Punitiveness and Devaluation among Social Work Gatekeepers

open access: yesSocial Work and Society, 2020
This paper analyses the connection between a punitive educational orientation and different negative prejudices in the context of group-focused enmity.
Johanna Pangritz, Wilhelm Berghan
doaj  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

November 2010 [PDF]

open access: yes, 2010
https://nsuworks.nova.edu/shss_dcar/1005/thumbnail ...
Department of Conflict Analysis and Resolution
core   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Winter 2015 [PDF]

open access: yes, 2015
https://nsuworks.nova.edu/shss_dcar/1010/thumbnail ...
Department of Conflict Analysis and Resolution
core   +4 more sources

September 2010 [PDF]

open access: yes, 2010
https://nsuworks.nova.edu/shss_dcar/1007/thumbnail ...
Department of Conflict Analysis and Resolution
core   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Conflict-related environmental degradation threatens the success of landscape recovery in some areas in Tigray (Ethiopia)

open access: yesEcology and Society
Armed conflicts can lead to environmental degradation, thereby threatening the basis of people’s livelihoods and well-being. Identifying areas where conflicts drive environmental degradation is important for designing effective recovery strategies, but ...
Henrike Schulte to Bühne   +4 more
doaj   +1 more source

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