Results 121 to 130 of about 4,205,966 (314)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
, 2018 In 2017 alone, an estimated 68,851 people lost their lives as a consequence of civil wars, that is, armed conflicts that take place within the borders of a state.
Deglow, Annekatrin
core
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Frontiers in SociologyIntroductionSeveral countries have experienced a shift toward the privatization and commodification of public goods, welfare policies, and social services.
Juan Carlos Castillo +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Frontiers in Political ScienceThis study investigates political efficacy—citizens’ beliefs in their ability to understand politics (internal political efficacy) and influence outcomes (external political efficacy)—in the context of town hall meeting (THMs) participation in a German ...
Yann P. M. Rees +4 more
doaj +1 more source
Governance and Conflict Relapse
, 2015 Many conflict studies regard formal democratic institutions as states’ most important vehicle to reduce deprivation-motivated armed conflict against their governments.
Nygård, Håvard,, Hegre, Håvard,
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Obrana a StrategieThe demand for significantly increased protection of civilians in the Gaza Strip from the consequences of Israeli military operations, together with reports of high civilian casualties, has resonated in public discourse for more than 18 months.
Veronika D´Evereux, Vojtěch Sedlák
doaj +1 more source