Results 141 to 150 of about 461,964 (264)

Enhancing emergency response in Somalia: Evaluating the WHO Mass Casualty Management course in trauma hospitals. [PDF]

Afr J Emerg Med
Ali MM, Ismail BM, Hussein M, Sydlowski MM, Michaeli N.   +4 more
europepmc   +1 more source

Voluntary Admission of Children to Mental Hospitals: a Conflict of Interest Between Parent and Child [PDF]

, 1976

core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Hospital functionality in the Gaza Strip: analysis of the World Health Organization health resources and services availability monitoring system database, 7 Oct 2023 to 31 Oct 2024. [PDF]

Confl Health
Mills D, Asi Y, Kunichoff D, Nelson E, Nasser J, Barkley S, Arias Delafosse R, Scher C, Tanous O, Hammoudeh W, Wispelwey B, Bahour N, Peeperkorn R, Evers E, Gonsalves L, Van Den Hoek J, Greenough PG.   +16 more
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Doctors' knowledge, attitudes, and practices in managing dengue fever amid war: A study in three governmental hospitals in Port Sudan, Red Sea State, Sudan (2024). [PDF]

SAGE Open Med
Ebrahim T, Saeed AA, Ali Allam WA, Badi S.   +3 more
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

The Implications of Private Equity Investment in Emergency Medicine. [PDF]

J Am Coll Emerg Physicians Open
Dilip M, Derse AR, Paxton JH, Martin DR.
europepmc   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

A multi-state cross-sectional assessment of essential medicine availability in Sudan during armed conflict. [PDF]

Sci Rep
Ahmed NO, Zamel AMA, Ahmed SG, Musa SE, Allah MMH, Alshami SM, Ali T, Almajeed MAAA, Elhassan NAM, Alhashmi M, Eisa LB, Shaar A, Khalifa SE, Abdalgader H, Saeed AA.   +14 more
europepmc   +1 more source