Results 121 to 130 of about 145,556 (272)

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

A Caring Class: Labor Conflict and the Moral Economy of Care in California Hospitals [PDF]

open access: yes, 2017
This dissertation examines the connections between the moral evaluation of caring labor and the patterns, practices, and potential effectiveness of hospital workers’ collective economic conflict in California hospitals over the latter 20th century.
Gaston, Pablo Uriarte
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Access to Church Records: Trinity Church, an Example

open access: yes, 1983
One of the constant problems facing archivists is the tension created between the twin goals of access and the right to privacy. As a result of state and national freedom of information acts and debate in the postWatergate era about sunshine laws, this ...
Barr, Phyllis
core  

The responsibility of the state on the violation of the rights of the child during the post-armed conflict : the case of the Democratic Republic of Congo [PDF]

open access: yes, 2012
Dissertation (LLM)--University of Pretoria, 2013.The United Nations General Assembly adopted on the 20PthP of November 1989 the Convention on the Rights of the Child responding to the atrocities committed against the child, the deaths of children from ...

core  

Opioid moderatism and the imperative of rapprochement in pain medicine

open access: yesJournal of Pain Research, 2019
Michael E Schatman,1,2 Alexis Vasciannie,3,4 Ronald J Kulich3,5 1Research and Network Development, Boston PainCare, Waltham, MA, USA; 2Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, USA; 3Department ...
Schatman ME, Vasciannie A, Kulich RJ
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Management Principles and Conflict Determinants in State and Federal Hospitals in South-South, Nigeria

open access: yesThe International Journal of Business & Management, 2019
Ighedose Lucky Ojiezele, Major Iteimowei
openaire   +2 more sources

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