Results 111 to 120 of about 145,556 (272)
Rest and restitution : convalescence and the public mental hospital in England, 1919–39 [PDF]
Previous histories have tended to look beyond the asylum for innovations in early twentieth-century mental healthcare. In contrast, this thesis appraises the mental hospital as the nexus for a new approach to convalescent care and makes the case for a
Soanes, Stephen
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O conflito no processo de trabalho da equipe de emergência [PDF]
, 2007 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-graduação em EnfermagemOs conflitos fazem parte da nossa vida pessoal e profissional.
Almeida, Paulo Jorge dos Santos
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
, 1988 This study compared the perceptions of interaction style of administrators of nursing and the Master\u27s prepared nurses working with them at eight hospitals in Tennessee to investigate the relationship of perceptions to job satisfaction, role ambiguity,
Nentrup, Randall L.
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Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
A/68/750-S/2014/91 (Promotion and Protection of the Rights of Children)
, 2014 The report discusses specific, concrete, and targeted actions that can be taken within the framework of the UN’s Children and Armed Conflict agenda to put an end to and to prevent the recruitment and use of children by state actors and non-state armed ...
Liechtenstein Institute on Self-Determination +2 more
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Journal of Education, Health and Sport, 2015 Shyschuk V. D., Kornus O. G., Kornus A. A., Shyschuk A. V. Регіональна система медичного обслуговування: сучасний стан і особливості функціонування (на прикладі Сумської області) = Regional health care system: current status and features of the ...
V. D. Shyschuk +3 more
doaj +2 more sources
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source