Results 201 to 210 of about 1,074,730 (257)

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

A novel endoscopic ultrasound system assisted by artificial intelligence for the recognition of pancreatic parenchyma and the detection of solid/cystic lesions. [PDF]

Endoscopy
Takahashi S, Takahashi T, Fujisawa T, Ikoma I, Jimbo Y, Tomishima K, Isayama H.   +6 more
europepmc   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Preeclampsia Among Pregnant Women Admitted to a Tertiary Care Hospital in Taiz City: Insights from a Conflict-Stricken Setting in Southwest Yemen. [PDF]

Int J Womens Health
Hasan HM, Thabit MSM, Abdulaziz M.
europepmc   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Nanostructural engineering presents an opportunity for next-generation multi-dimensional camouflage. [PDF]

Light Sci Appl
Wei B, Du J.
europepmc   +1 more source

On Multi-Parameter Optimization and Proactive Reliability in 5G and Beyond Cellular Networks. [PDF]

Sensors (Basel)
Ijaz A, Raza W, Riaz S, Imran A.
europepmc   +1 more source

Comment on the "Evaluation of sensory loss in the feet and associated factors in ambulatory patients with diabetes: a cross-sectional study". [PDF]

Arch Endocrinol Metab
Gao H.
europepmc   +1 more source

Diagnostic and prognostic value of serum markers CEA, CA50, CA19-9, CA72-4, and CYFRA21-1 in colon cancer. [PDF]

J Med Biochem
Song Z, Tang J, Wu M, Li Z, Zhang Y.
europepmc   +1 more source