Results 71 to 80 of about 708,361 (267)

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Conflict Management Styles in Croatian Enterprises – The Relationship between Individual Characteristics and Conflict Handling Styles [PDF]

The objective of the paper, except determining the dominant conflict handling style in Croatian organizational setting, was to explore individual characteristics affecting the choice of conflict resolution style of Croatian employees.
Nina Pološki Vokić, Sanja Sontor
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Conflict management in family businesses: A bibliometric analysis and systematic literature review [PDF]

, 2018
Purpose – The purpose of this study is to map the intellectual structure of the field of conflict management and the field of family business to the investigation of conflicts in family firms, with the aim of contributing to the further integration of ...
Marzi, G, Pellegrini M, Rialti R., Rialti, R, Riccardo Rialti, Caputo A, Pellegrini M., Marzi G, Giacomo Marzi, Pellegrini M. M., Rialti R, Pellegrini, M, Andrea Caputo, Marzi G., Massimiliano Matteo Pellegrini, Caputo, A, Caputo A.   +16 more
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Environmental conflict and decision-making: the case of hydroelectric power

, 2012
As management of the environment becomes more complex and the number of potentially conflicting issues to be balanced expands, there will be increasing and more intense debates about the course(s) of action(s) to be taken.
Watkin, L, Watkin, L.
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Informal Conflict Management in Exclusivist Political Orders: Some Observations on Central Mindanao

ASEAS - Austrian Journal of South-East Asian Studies, 2014
In the past decade, a range of international and national NGOs have pointed to the need to complement national-level negotiations with a support for alternative, informal institutions of conflict management in order to reach a sustainable peace in the ...
Jeroen Adam, Boris Verbrugge
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

THE EVOLUTION OF CONFLICT AS A BEHAVIOR PROCESS WITHIN GLOBAL ORGANIZATIONAL COMMUNICATION MANAGEMENT [PDF]

Nowadays, organizations are designed so that it can carry out their various activitiesnecessary to face the uncertainty surrounding each of them. The consequences of these actions arereflected in differences between departments and a greater potential ...
Elida-Tomita Todarita
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Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

The Macedonian Crisis – A failure of EU conflict management? CEPS Commentary, 5 May 2017 [PDF]

, 2017
In the Global Strategy for the European Union’s Foreign and Security Policy, there is a chapter devoted to “An Integrated Approach to Conflicts and Crises”.
Fouéré, Erwan
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