Results 111 to 120 of about 1,248,632 (310)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Harnessing the Power of Focal Points To Measure Social Agreement [PDF]

This paper reports results from an application of Thomas Schelling’s (1960) concept of a focal point to the measure of social agreement on the received tone of media content.
Stuart Soroka, Jim Engle-Warnick
core  

Neural-behavioral dissociation under acute high-altitude stress: an exploratory ERP study of non-specific neural recruitment and rTMS effects

Frontiers in Behavioral Neuroscience
ObjectiveAcute high-altitude hypobaric hypoxia impairs executive functions, yet the dynamic relationship between behavioral performance and neuroelectric activity remains unclear.
Peng Wu, Peng Wu, Peng Wu, Peng Wu, Lizhi Liu, Lizhi Liu, Lizhi Liu, Huanhuan Li, Huanhuan Li, Huanhuan Li, Jiangheng Guan, Jiangheng Guan, Yang Lu, Yang Lu, Yang Lu, Xianglin Kong, Xianglin Kong, Xianglin Kong, Jian Song, Jian Song, Jian Song, Jian Song, Jian Song, Guozheng Xu, Guozheng Xu, Guozheng Xu, Guozheng Xu, Guozheng Xu   +27 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

An Optimal Vehicle-Scheduling Model for Signal-Free Intersections Considering Bus Priority in a Connected and Automated Vehicle Environment

Sensors
The optimal scheduling of vehicles at signal-free intersections under the connected and automated vehicle (CAV) environment has become a research hotspot in the intelligent transportation field.
Dongliang Wang, Shunjie Jiang, Guorong Zheng, Xiaohu Shi   +3 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

An exploration of conflict handling among Quakers

The Quaker community is committed to conflict resolution; it might be expected that the community itself is conflict free. This study explores this proposition and presents a counter narrative: conflict does exist among Quakers, with its roots in the ...
Robson, Susan Margaret
core  

Post-conflict transition and development in Sierra Leone: a case for the transformative-justice model

, 2011
Includes abstract.Includes bibliographical references.The focus of this mini-dissertation is the Sierra Leone post-conflict transitional and development process. The civil war in Sierra Leone lasted some eight years before finally ending with the signing
Connolly, Lesley Frances
core  

Rahim Organizational Conflict Inventory: Instrumentation and Application for Extension Professionals

EDIS
Conflict is inevitable in workplaces among people of all ages. Extension professionals have a unique position where in a single workday they may be engage with youth and volunteers, as well as colleagues and supervisors.
Christy Chiarelli, Anne Parrish, Megan Cantrell, Matt Benge   +3 more
doaj  

Analysis on the Conflicting Points of the Locational Conflict [PDF]

Korean Journal of Policy Studies, 2001
openaire   +1 more source